Threshold Pharmaceuticals, Inc.

Immunogenesis, Inc.

John G Curd

Mark D Matteucci

Jian-Xin Duan

Charles Praray Hart

Stewart Kroll

Jessica D Sun

Charles P Hart

Cancer can be treated by administration of a hypoxia-activated prodrug, such as TH-302, alone or in combination with other anticancer agents and/or radiation therapy. In combination therapy, the hypoxia-activated prodrug and another anti-cancer agent or radiation therapy may be administered within the same 24-hour period, and administration of the hypoxia-activated prodrug may be completed prior to beginning administration of the other anticancer agent or radiation therapy.

Treatment of cancer using hypoxia activated prodrugs

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Burlingame, CA, United States of America

John G Curd