Arixa Pharmaceuticals, Inc.

John Freund

Eric M Gordon

Matthew A J Duncton

Mark A Gallop

Matthew Alexander James Duncton

Matthew A Duncton

Matthew Aj Duncton

Disclosed herein are aztreonam derivatives, therapeutic methods of using the aztreonam derivatives, and methods of synthesizing aztreonam derivatives. The aztreonam derivatives can be administered orally to provide orally bioavailable aztreonam.

Methods of synthesizing aztreonam derivatives

Derivatives of relebactam, therapeutic methods of using the derivatives of relebactam, particularly in combination with &#x3b2;-lactam antibiotics and pharmaceutical compositions thereof are disclosed. The derivatives of relebactam are suitable for oral administration.

Derivatives of relebactam and uses thereof

Disclosed herein are aztreonam derivatives, therapeutic methods of using the aztreonam derivatives, particularly in combination with &#x3b2;-lactamase inhibitors, and pharmaceutical compositions thereof. The aztreonam derivatives can be administered orally to provide orally bioavailable aztreonam.

Aztreonam derivatives and uses thereof

&#x3b2;-Lactamase inhibiting compounds, therapeutic methods of using the &#x3b2;-lactamase inhibiting compounds, particularly in combination with &#x3b2;-lactam antibiotics and pharmaceutical compositions thereof are disclosed. The &#x3b2;-lactamase inhibiting compounds are suitable for oral administration.

Growing community of inventors

Atherton, CA, United States of America

John Freund