Mogen International Nv

Rijksuniversiteit Te Leiden

Rijksuniversiteit Leiden

John Ferdinand Bol

Bernardus Johannes Cornelissen

Leo Sjoerd Melchers

Marianne Beatrix Sela-Buurlage

Hubertus J Linthorst

Elisabeth J Meulenhoff

Charles Peter Woloshuk

Jeroen S Van Roekel

Alexandra Aleida Vloemans

Anne Silene Ponstein

Marion Apotheker-De Groot

Johannes A Van Kan

Plants are provided with improved resistance against pathogenic fungi. They are genetically transformed with one or more polynucleotides which essentially comprise one or more genes encoding plant chitinases and .beta.-1,3-glucanases. Preferred are the intracellular forms of the said hydrolytic enzymes, especially preferred are those forms which are targeted to the apoplastic space of the plant by virtue of the modification of the genes encoding the said enzymes. Particularly preferred are plants exhibiting a relative overexpression of at least one gene encoding a chitinase and one gene encoding a .beta.-1,3-glucanase.

Transgenic fungal resistant plants expressing chitinase and glucanase,

Chitinase, DNA coding therefor and plants containing same

Fungal resistant plants, process for obtaining fungal resistant plants

This invention relates to recombinant DNA comprising vector-DNA and a DNA sequence corresponding with, or relates to, a salicylate-inducible promoter of a GRP gene of plants, such as tobacco plants. The invention also relates to microorganisms, plant cells and plants transformed using the recombinant DNA, to a process for introducing an inducible property in plants and to a process for producing a polypeptide or protein, using plant cells and plants transformed using the recombinant DNA.

Recombinant DNA: transformed microorganisms, plant cells and plants: a

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Oegstgeest, Netherlands

John Ferdinand Bol