Smithkline Beecham Corporation

John F Newton

John G Gleason

Jerry Leroy Adams

Paul E Bender

Ralph F Hall

Carl D Perchonock

Nabil Hanna

Joanne Smallheer

Kathleen A Phipps

Kazys A Razgaitis

This invention relates to certain 2-substituted benzaldehydes which are useful intermediates for preparing certain diacids which are useful as leukotriene antagonists.

Ortho-substituted benzaldehydes

Compounds comprising pyridyl and phenyl substituted pyrrolo[1,2-a]imidazole derivatives and pyridyl and phenyl substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing said compounds, and their use as 5-lipoxygenase pathway inhibitors.

Pyrrolo [1,2-a] imidazole and imidazo [1,2a] pyridine derivatives and

Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their

This invention relates to ester prodrugs for alkanoic acid compounds useful as leukotriene antagonists, and pharmaceutical compositions containing such ester prodrug compounds. This invention also relates to methods of treating diseases in which leukotrienes are a factor by administration of an effective amount of the above compounds or compositions.

Ester prodrugs

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West Chester, PA, United States of America

John F Newton