University of Louisville Research Foundation, Inc.

Biolink Systems, LLC

Other

California Institute of Technology

University of California

Orthodata Technologies LLC

Advanced Ophthalmics LLC

Neurorecovery Technologies, Inc.

4th & Exactly LLC

John F Naber

Douglas J Jackson

Robert S Keynton

Doug Jackson

Kevin M Walsh

Susan Jill Harkema

Roger King

Claudia A Angeli

Thomas Roussel

Yu-Chong Tai

Victor Reggie Edgerton

Yury P Gerasimenko

Joel W Burdick

Roland R Roy

Nicholas A Terrafranca

Mandheerej S Nandra

Thomas Anthony Desautels

Jonathan Hodes

Mark Crain

Yangsheng Chen

Steven L Upchurch

Jason Heyl

Scott Douglas Cambron

Thomas J Roussel, Jr

Ken Heyl

Michael J Martin

Manikandan Ravi

Richard P Baldwin

Yangshen Chen

Glen Haire

Michael Calvin McCoy

Richard Bernard Hageman, Iii

William P Hnat

Suraj Alexander

Rathissh Dorairaj

Saliya Kirigeeganage

Rich Eiferman

Jeff L Lee

Ji-Tzuoh Lin

William Hnat

Christopher Isert

Danielle B Franco

Julia W Abersold

Jr Nicholas A Terrafranca

Patients with spinal cord injuries have benefited from neurostimulation therapy comprising delivery of electrical stimulation to enable or excite neurological responses using an implantable neurostimulator having an electrode array. Dangerous levels of charge are avoided while providing multiple, simultaneous stimulation waveforms by inducing a short in an electrode when a monitored value reaches or exceeds a predetermined threshold.

Methods for neurostimulator pulse overlap control

A clip-on module having a specialized housing design, probe contacts, switches, various advertising modes, and various configurations of signal repeaters is disclosed. The module is utilized via attachment to a specialized garment worn by a human patient. To properly apply the housing to the garment, a user will squeeze the module to open using tactile features embedded within the housing, locate the module, and then press-clamp the module to close and attach it. A plurality of probe contacts within the module have sharpness requirements for penetrating one or more layers of the garment while still maintaining low resistance, and will work with a backing material for probe.

Clip on electronics module

Module-housing system and method

An incontinence detection device and system is disclosed.

Incontinence system

Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.

Methods for providing optimized neurostimulation

A system and method for remotely monitoring Inter Ocular Pressure (IOP) is disclosed. The system and method verify proper operation of glaucoma drainage, measure and potentially affect Intra-Ocular Pressure (IOP), and facilitate remote disease management of e.g. glaucoma, among other ocular diseases.

Ocular system and method

Various methods for detecting moisture in briefs compatible with high volume manufacturing are disclosed. The embodiments herein facilitate protection of the method of adding moisture sensing to a diaper, but could also be used to add sensing to pads and bandages. The primary design intent is optimal moisture detection and low per unit cost. Electrodes within a garment measure electrical properties of the electrodes to determine if the item has contacted moisture. The target moisture is urine, however, other sources and types of moisture can also be sensed. Additional analysis capabilities can be added by selecting particular electrodes or add materials that may react with chemical components of the moisture. Applications of the research Include monitor of incontinence using smart brief (e.g. diaper); monitor perspiration, bleeding, or failure of the protective garment; and monitoring exposure of an item to moisture, including but not limited to inanimate items.

Garment manufacturing system and method

Neurostimulator devices are described. An example neurostimulator device includes a stimulation assembly connectable to a plurality of electrodes, wherein the plurality of electrodes are configured to stimulate a spinal cord. The neurostimulator device also includes an interface and at least one processor configured to modify at least one complex stimulation pattern deliverable by the plurality of electrodes by integrating data from the interface and performing a machine learning algorithm on the at least one complex stimulation pattern.

Neurostimulator

Neurostimulator devices are described comprising: a stimulation assembly connectable to a plurality of electrodes, wherein the plurality of electrodes are configured to stimulate a spinal cord; one or more sensors; and at least one processor configured to modify at least one complex stimulation pattern deliverable by the plurality of electrodes by integrating data from the one or more sensors and performing a machine learning method implementing a Gaussian Process Optimization on the at least one complex stimulation pattern. Methods of use are also described.

Neurostimulator devices using a machine learning method implementing a gaussian process optimization

Described are devices including stimulation assemblies connectable to a plurality of electrodes. The plurality of electrodes can be configured to connect to a spinal cord at a location below a lesion of the spinal cord. The stimulation assembly can be configured to deliver stimulation to selected ones of the plurality of electrodes when the stimulation assembly is connected to the plurality of electrodes when located below the lesion of the spinal cord. Methods of using the devices are also described.

Spinal stimulator systems for restoration of function

A large volume preconcentrator device for concentrating analytes. A housing accepts an analyte vapor flow, and a plurality of collection surfaces are disposed within the housing. A selectively actuatable heater is disposed on each of the plurality of collection surfaces. At least one selectively actuatable damper is disposed within the housing for selectively restricting a collection flow.

Large volume analyte preconcentrator

An interchangeable preconcentrator assembly comprises an outer housing and an inner housing defining a chamber. A biased urging member is held at least partially within the outer housing and slidably biased toward a surface of the inner housing. When the biased urging member is at least partially retracted, a space is defined between the urging member and the surface of the inner housing for accommodating at least one preconcentrator chip. A continuous fluid flow path is defined through the outer housing and through the space. The interchangeable preconcentrator assembly may further comprise at least one modular preconcentrator carriage.

Interchangeable preconcentrator connector assembly

Growing community of inventors

Prospect, KY, United States of America

John F Naber