Oratec Interventions, Inc.

Howmedica Osteonics Corporation

Benvenue Medical, Inc.

Coalign Innovations, Inc.

Puracath Medical, Inc.

Neurotherm, Inc.

Baxano, Inc.

Anpa Medical, Inc.

Ostovalve, LLC

Auctus Surgical, Inc.

Amendia, Inc.

Mitrx, Inc.

Covidien LP

Syneron Medical Ltd.

Spinal Kinetics, Inc.

John E Ashley

Hugh R Sharkey

Joel Stuart Saal

Jeffrey Alan Saal

Le Trong Le

Walter Dean Gillespie

Philip Simpson

Rudy A Pretti

George Albert Mansfield

Murali P Kadaba

Laurent B Schaller

Jeffrey L Emery

James K Lee

J Brook Burley

Timothy J McGrath

Ryan Jeffrey Connolly

David G Matsuura

Jeffrey Wayne Etter

Vahid Saadat

Jochen P Backs

Jeffery Lee Bleich

Albert K Chin

James E Jervis

John B Simpson

Michael Lawrence Reo

Michael H Rosenthal

Darin Charles Gittings

Kenneth J Michlitsch

Larry T Khoo

David Frederick Lyons

Darren G Doud

Huy D Phan

Janine C Robinson

Sepehr Fariabi

Daren Stewart

Uriel Hiram Chee

Gary S Fanton

Bruno Strul

Michael George Fourkas

Bankim H Mehta

Thomas Grotz

Damien J Shulock

Steven Golden

David Needleman

Hugh J Sharkey

Julia A Rasooly

Andy Uchida

Damien Shulock

Ian Tran

Dennis Crandall

Justin Aaron Lance

Stephen Nicholas Bower

John Barrett

Michael Rasooly

George A Mansfield, Jr

Robert C Bell, Jr

Benjamin Scott Arnett

Gary J Margolis

J Remberto Carranza

Jeff A Saal

Kobi Iki

Steven A Spisak

Philip J Simpson

Gautama B Venegas

Ramiro L Reyes

Murali Dharan

Nicholas C Koske

Kevin To

Elizabeth V Wistrom

Scott A McGILL

Timothy J Mcgrath

David S Needleman

George A Iii Mansfield

Benjamin Arnett

George A Mansfield

Brook J Burley

Walter D Gillepie

Thomas R Grotz

Roxanne L Richman

Hand held and portable disinfection units for use with patients having indwelling catheters or are hospitalized or under care in an intensive care unit.

Point of care ultraviolet disinfection system

A medical appliance is configured with material that creates a fluid barrier with interior walls of a stoma on a patient. These configurations may include an annular disc with a stem on one side that inserts into the stoma. The material may reside on the stem, for example, in the form of a replaceable hollow tube that covers at least part of the stem. On the other side, a rotatable spigot inserts into a recess. The rotatable spigot has a first position that forms a flow path through the stem and the annular disc to allow waste to drain from the stoma. In one implementation, the rotatable spigot can couple with a collection device that receives the waste. The patient can return the rotatable spigot to a second position to prevent flow of waste.

Devices, systems and methods for regulating flow from a stoma on a patient

Spinal curvature modulation systems, methods and related devices and instrumentation are disclosed, which include a flexible tether, a tether tensioning unit and bone anchors for the flexible tether that allow the tether to be secured across multiple vertebrae in a region of treatment. When the flexible tether is attached to multiple vertebrae, it can be used to correct spinal deformities. Tension in the flexible tether is adjustable transcutaneously without invasive surgical procedures by use of remotely driven actuators, such as a magnet-driven motor, or by a small tool insertable through a small incision. Disclosed systems and methods thus allow for multiple adjustments of tether tension, and spinal curvature, over time without repeated, highly invasive, spinal surgeries.

Spinal curvature modulation systems and methods

A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning.

Lockable spinal implant

Systems and methods of disinfection of catheter connections are provided. A transfer catheter connector can include a UV-transparent window at its distal end and a sealing plunger proximal to the UV-transparent window. A solution set connector can be inserted inside a portion of the transfer catheter connector to connect a solution set and transfer catheter. The solution set connector comprises a lumen covered by a leading membrane surface; a sealing surface configured to sealingly engage the window surface, and a piercing member configured to pierce the membrane surface. The sealing plunger, membrane surface, and window define a disinfection zone. The connectors can be connected in a disinfection position configuration in which flow is not permitted between the catheters and the connectors are irradiated with UV light. After disinfection, the connectors are advanced to a flow position in which the piercing member pierces the membrane surface, enabling flow between the catheters.

Catheter connection system for ultraviolet light disinfection

A selectively expanding spine cage has a minimized cross section in its unexpanded state that is smaller than the diameter of the neuroforamen through which it passes in the distracted spine. The cage conformably engages between the endplates of the adjacent vertebrae to effectively distract the anterior disc space, stabilize the motion segments and eliminate pathologic spine motion. Expanding selectively (anteriorly, along the vertical axis of the spine) rather than uniformly, the cage height increases and holds the vertebrae with fixation forces greater than adjacent bone and soft tissue failure forces in natural lordosis. Stability is thus achieved immediately, enabling patient function by eliminating painful motion. The cage shape intends to rest proximate to the anterior column cortices securing the desired spread and fixation, allowing for bone graft in, around, and through the implant for arthrodesis whereas for arthroplasty it fixes to endpoints but cushions the spine naturally.

Selectively expanding spine cage with enhanced bone graft infusion

Hand held and portable disinfection units for use with patients having indwelling catheters hospitalized or under care in an intensive care unit.

Systems, devices, and methods for endoscopically retracting a target tissue. The device includes a first shaft and a second shaft slidably coupled thereto. An internal member extends in a transverse direction from the first shaft and is configured for advancement through a penetration in the target tissue to atraumatically engage a distal surface of the target tissue after being advanced therethrough. A pair of external members extend from the second shaft generally parallel to the transverse direction. The external members are spaced apart and are configured to atraumatically engage a proximal surface of the target tissue when the internal member is moved longitudinally relative to the external members. The internal member applies traction to the target tissue when retracted past the pair of external members, which apply counter-traction to the target tissue on opposing lateral sides of the internal member, to re-shape the target tissue and enable subsequent suture placement.

Pursestring suture retractor and method of use

Adjustable distraction cage with linked locking mechanisms

Systems and methods of disinfection of catheter connections are provided. A transfer catheter connector can include a UV-transparent window at its distal end and a seal proximal to the window. A solution set connector can be inserted inside a portion of the transfer catheter connector to connect a solution set and transfer catheter. The solution set connector comprises a lumen covered by a leading membrane surface; and a sealing surface configured to sealingly engage the window surface. The connectors can be connected in a disinfection position configuration in which flow is not permitted between the catheters and the connectors are irradiated with UV light. After disinfection, the connectors are advanced to a flow position in which the piercing member pierces the membrane surface, enabling flow between the catheters. The system comprises clips that prevent advancement to the flow position without interference by the disinfection unit or by a user.

An insertion handle for medical implants includes a handle with an elongate shaft extending therefrom and connection means for the implant disposed at the end of the shaft opposite the handle. The connection means includes a pivotable attachment for the implant that is controlled remotely from the handle. Both angle of the implant with respect to the handle and shaft as well as the attachment may be separately controlled and adjusted. Remote angular adjustment facilitates insertion of implants in to small surgical sites because the orientation of the implant may be repeatedly, remotely adjusted as the implant is inserted. Connectors may also be provided at the engagement surface between the handle and implant in order to provide communication with the implant or surgical site. The connectors also may serve as torque bearing members to avoid the need for separate torque bearing means such as keyways and the like.

Insertion handle for surgical implants

Growing community of inventors

San Francisco, CA, United States of America

John E Ashley