Other

Joint Medical Products Corporation

Bobyn, John Dennis

Tanzer, Michael

John Dennis Bobyn

Alfred F DeCarlo, Jr

Michael Tanzer

Jan Janusz Krygier

Michael Tanzar

Caleb Emerson Brooks

Alfred F Decarlo

A bone implant comprises an active agent on at least a portion thereof. The active agent is locally deliverable to bone proximate the implant in at least a two-phased release scheme. A first phase rapidly releases a first quantity of the active agent, and at least a second phase gradually releases a second quantity of the active agent, whereby bone formation stimulated by the active agent is modulated. In one embodiment, a porous implant comprises a porous portion coated with a calcium phosphate compound and which is contacted with a bisphosphonate compound to form a bisphosphonate layer chemically bound to the calcium phosphate at the surface of the porous portion and to form bisphosphonate molecules being non-chemically attached inside the pores of the porous portion. The non-chemically attached bisphosphonate molecules are released in the subject at a rate greater than that of the chemically bound bisphosphonate layer.

Implant improving local bone formation

Prosthetic joint system for bone replacement

Growing community of inventors

Westmount, Canada

John Dennis Bobyn