Imperial Chemical Industries Limited

Zeneca Limited

Other

John David Jones

Brian Geoffrey Cox

David Schofield

Jan Michael Fielden

Gareth Andrew DeBoos

Paul Wilkinson

Stephen Martin Brown

Martin Charles Bowden

Alan T Costello

Maria Jones

A new cultivar ofplant named 'HYFJOLAIS' that is characterized by its short stem internodes, its leaves that are dark in color, its flowers that are distinct from foliage and white in color with burgundy and pink highlights, and its compact plant habit.

plant named 'HYFJOLAIS'

A new cultivar of, 'JONIGHT' that is characterized by its compact, upright and bushy plant habit, its foliage that is very dark purplish-brown to black in color, and its well branched stems with short internodes.

plant named 'JONIGHT'

A process for the preparing agrochemical intermediates of formula (I): ##STR1## wherein W is (CH.sub.3 O) CH.CHCO.sub.2 CH.sub.3 or CH.sub.3 O.CH.dbd.CCO.sub.2 CH.sub.3 ; Z.sup.1 is a halogen atom; and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, acetoxy or acyl; the process comprising the steps of:

Chemical process

Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, acetoxy or acyl, and processes for preparing the same.

Process for the preparation of

Process for the preparation of 4,6-dichloropyrimidine

A process of preparing the compound of formula (I): ##STR1## which comprises reacting butyryl chloride with the compound of formula (III): ##STR2## in the presence of a Friedel-Crafts catalyst, in an inert diluent.

Process for preparing

A process for preparing a compound of formula: ##STR1## where R.sup.1 is halogen, CF.sub.3 or methyl; which process comprises decarboxylation of a compound of formula (III): ##STR2## where R.sup.1 is as defined above and R.sup.3 is hydrogen or a cation. Compounds of formula (III) and processes for their preparation are also claimed.

Quinazolin-2-ones

A process for the production of a substituted amide of the formula: ##STR1## where R.sup.1 is an optionally substituted aryl group, X.sup.1 is --O-- or --S-- and R.sup.2 is an optionally substituted alkyl, alkenyl, or alkynyl group or X.sup.1 R.sup.2 is an N-linked 5-membered nitrogen heterocycle comprising the halogenation, preferably bromination, in an inert solvent of a N-cyanomethyl-amide of the formula R.sup.1 --CONH.CH.sub.2 CN, followed by addition to the halogenated mixture, or to the mixture as halogenation is taking place, of a heterocyclic tertiary amine in a proportion of from about 1.0 to about 2.5 moles, and preferably from 1.3 to 2.1 moles, for each mole of halogen reacted, and finally treatment of the resulting quaternary salt with an alcohol, thiol or amine of the formula R.sup.2 X.sup.1 H.

Benzamides of the formula (I): ##STR1## in which Ar is optionally substituted aryl; X is O, S or NH and R is optionally substituted alkyl or alkenyl when X is O or S, or is optionally substituted alkanoyl when X is NH, are prepared by

Substituted benzamides

Bromoacetamides of the formula ArCONHCH(Br)CONH.sub.2 are obtained by addition to bromine of a solution of ArCONHCH.sub.2 CN in a saturated aliphatic carboxylic acid preferably glacial acetic or propionic acid. This is an improvement in a process described in European Patent Specification No. 0059536 in which the bromine is added to a solution of the cyanomethylbenzamide, enabling consistently high yields (e.g. 75 to 90%) to be obtained.

Preparation of bromoacetamides

Benzamides of the formula (I): ##STR1## in which Ar is optionally substituted aryl; X is O, S or NH and R is optionally substituted alkyl or alkenyl when X is O or S, or is optionally substituted alkenoyl when X is NH, are prepared by

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Bury, United Kingdom

John David Jones