Massachusetts Institute of Technology

The General Hospital Corporation

Commonwealth Fusion Systems LLC

Other

Massachusetts General Hospital Corporation

Interform, Inc.

John D Wright

Zachary S Hartwig

Philip Michael

Rui Vieira

Brandon N Sorbom

William Beck

Martin Greenwald

Robert Mumgaard

James Irby

Daniel Brunner

Brian Labombard

Robert S Granetz

Lihua Zhou

Jeffrey Doody

Alexey L Radovinsky

E Antonio Chiocca

Thomas S Deisboeck

Syun'ichi Shiraiwa

Shunichi Shiraiwa

Ronald S Newbower

Jose G Venegas

Alan R Shapiro

Martha L Gray

Luis A Melendez

Alexey Radovinsky

Jonathan L Schaffer

Jeffrey A Secunda

Robert H Burroughs

Described herein are concepts, system and techniques which provide a means to construct robust high-field superconducting magnets using simple fabrication techniques and modular components that scale well toward commercialization. The resulting magnet assembly—which utilizes non-insulated, high temperature superconducting tapes (HTS) and provides for optimized coolant pathways—is inherently strong structurally, which enables maximum utilization of the high magnetic fields available with HTS technology. In addition, the concepts described herein provide for control of quench-induced current distributions within the tape stack and surrounding superstructure to safely dissipate quench energy, while at the same time obtaining acceptable magnet charge time. The net result is a structurally and thermally robust, high-field magnet assembly that is passively protected against quench fault conditions.

Grooved, stacked-plate superconducting magnets and electrically conductive terminal blocks and related construction techniques

A building framework is disclosed herein having a first structural member, a second structural member, and a third structural member disposed between the first and second structural members, a first web member connecting the first and third structural members in a spaced apart relationship, and a second web member connecting the second and third structural members in a spaced apart relationship. The first web member is positioned relative to the second web member such that the shortest distance between the first web member and second web member is greater than or equal to 5 times the thickness of the third structural member. Additional products, systems, and methods also are disclosed.

Insulatable, insulative framework apparatus and methods of making and using same

Described herein are concepts, system and techniques which provide a means to construct robust high-field superconducting magnets using simple fabrication techniques and modular components that scale well toward commercialization. The resulting magnet assembly&#x2014;which utilizes non-insulated, high temperature superconducting tapes (HTS) and provides for optimized coolant pathways&#x2014;is inherently strong structurally, which enables maximum utilization of the high magnetic fields available with HTS technology. In addition, the concepts described herein provide for control of quench-induced current distributions within the tape stack and surrounding superstructure to safely dissipate quench energy, while at the same time obtaining acceptable magnet charge time. The net result is a structurally and thermally robust, high-field magnet assembly that is passively protected against quench fault conditions.

Grooved, stacked-plate superconducting magnets and electrically conductive terminal blocks

A building framework is disclosed herein comprising a first structural member, a second structural member, and a third structural member disposed between the first and second structural members, a first web member connecting the first and third structural members in a spaced apart relationship, and a second web member connecting the second and third structural members in a spaced apart relationship. The first web member is positioned relative to the second web member such that the shortest distance between the first web member and second web member is greater than or equal to 5 times the thickness of the third structural member. Additional products, systems, and methods also are disclosed.

A twine cutting apparatus in combination with an automated grass baler having a twine holding reel for feeding wrapping twine to the baled grass. The apparatus has a pivoted knife arm with a first end structured to cooperate with a cam surface for actuating the knife arm to a cutting position and an opposite end for mounting a twine cutting knife. The twine cutting knife is formed with an elongated, serrated cutting edge extending a distance greater than the radius of the twine holding disc presenting an elongated cutting surface to said twine.

Twine cutting knife for square baler apparatus

The invention relates to devices and methods for growing cells in vitro in an enclosed device that allows for a three-dimensional measurement over time of both their proliferative and/or invasive properties. By growing the cells in an enclosed matrix that resembles the environment that the cells confront in vivo, the cells can divide, invade, and form branched networks as they do in living tissue, e.g., in an individual. The devices of the invention include a test chamber in which cells, e.g., tumor cells, are placed and permitted to divide and/or invade. Cells can be placed within an insert within a chamber of the device. A delivery chamber that connects to the test chamber enables the delivery of agents that can be studied, e.g., for their therapeutic potential. The assay devices of the invention can be used as model systems to study cancer biology and to evaluate the efficacy of anti-cancer therapeutics.

Three-dimensional cell growth assay

Disclosed is an apparatus and method for imparting to a living culture of cells biaxial mechanical forces which approximate the mechanical forces to which cells are subjected in vivo. The apparatus includes a displacement applicator which may be actuated to contact and stretch a membrane having a living cell culture mounted thereon. Stretching of the membrane imparts biaxial mechanical forces to the cells. These forces may be uniformly applied to the cells, or they may be selectively non-uniformly applied.

Cell stretching apparatus

A system designed to enable persons incapable of manipulating a writing implement to sign papers and/or documents comprising a holder for the document to be signed, a holder for a transfer sheet for holding the transfer sheet adjacent that portion of the document to be signed and an implement defining the signature to be applied to the document for pressing the transfer sheet into transferring engagement with the document.

Hand printer designed to enable a handicapped person to apply a

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Sandown, NH, United States of America

John D Wright