Biomerieux, Inc.

Biofire Defense, LLC

Biom{tilde Over (e)}rieux, Inc.

John D Walsh

Jones M Hyman

Christopher S Ronsick

Mark S Wilson

Thurman C Thorpe

Bradford G Clay

Kirk M Ririe

Ryan T Hill

Ronnie J Robinson

Robert J Mowris

Scott R Jeffrey

James L DiGuiseppi

Michael Ullery

Diederik Engbersen

Erin Mathias

Ron Robinson

John G Link

Maud Arsac

Parampal Deol

James Shum Lau

Victoria Girard

Elizabeth Miller

Amber Gates

Sandrine Mailler

A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.

Isolation tube

Isolation tube woth and endcap

An occupancy fan control method to detect a Heating, Ventilating Air Conditioning (HVAC) fan is operating based on a fan-on duration control selected by a user and after a fan-on time delay selected by the user, providing at least one fan-on alarm message prior to overriding the fan-on duration control. The method further comprises monitoring an occupancy sensor signal to determine an occupancy in a conditioned space served by an HVAC system and after the fan-on time delay selected by the user, automatically overriding the fan-on duration control to save energy when the conditioned space is unoccupied. The overriding may comprise operating the HVAC fan based only on a thermostat call for cooling or heating, operating the HVAC fan for a non-zero time less time than the fan-on duration control, or operating the HVAC fan for a non-zero frequency less than the fan-on duration control.

Occupancy fan controller

The ionizer feedback control converts high-voltage signals to feedback signals to monitor the corresponding high-voltage signals and compares the feedback signals to a first specification to determine whether the feedback signals are within the first specification. The ionizer varies a frequency and a duty cycle of a digital signal to control an excitation signal for a step-up transformer and modulates the frequency and the duty cycle of a step-up transformer output voltage to consistently maintain the feedback signals within the first specification and maintain the high-voltage signals within a second specification to generate consistent ion concentrations over a range of electrical signal inputs. The microprocessor calculates and reports high-voltage signals, and ion concentrations based on feedback signals. The microprocessor monitors concentrations of Volatile Organic Compounds (VOCs) in an airflow serving the ionizer and adjusts the high-voltage signals and ion concentration when VOC concentrations are above a threshold.

Ionizer feedback control

Assembly comprising a sample collection vessel and a separation container having seal, plunger with seal-piercing point, retainer, and flexible sealing member

A Heating, Ventilating Air Conditioning (HVAC) fan control method to detect an HVAC fan is controlled by at least one fan-on duration control selected by a user and provide at least one fan-on alarm message prior to overriding the at least one fan-on duration control. The method monitors an occupancy sensor signal to determine an occupancy in a conditioned space served by an HVAC system and automatically overrides the at least one fan-on duration control to save energy when the conditioned space is unoccupied. The overriding may comprise operating the HVAC fan based only on a thermostat call for cooling or a thermostat call for heating, operating the HVAC fan for less time than the at least one fan-on duration control selected by the user, and operating the HVAC fan for less frequency than the at least one fan-on duration control selected by the user.

Occupancy-based fan control

Isolation tube with an endcap

Centrifugally separating samples in a container having a seal and containing a plunger for opening the seal

Isolation tube with a rheological control member and a plunger

The present invention relates to methods and systems for determining the antibiotic-resistance status of microorganisms. The invention further provides methods for determining the antibiotic-resistance status of microorganisms in situ within a single system.

Methods for antimicrobial resistance determination

The present invention is directed to methods and kits for separating, accumulating, characterizing and/or identifying microorganisms known to be present or that may be present in a test sample. The method of the invention comprises optional lysing non-microorganism cells and/or particulates that may be present in a test sample, followed by a subsequent filtration step for isolation and/or accumulation of microorganisms. The kit of the present invention may comprise at least one filter membrane or an integrated filtration and sample transfer device for isolation and/or accumulation of microorganisms.

Methods and kits for isolating microorganisms from culture

Growing community of inventors

Durham, NC, United States of America

John D Walsh