Other

Beth Israel Deaconess Medical Center, Inc.

Massachusetts Institute of Technology

The Children's Hospital of Philadelphia

John D Idoine

John V Frangioni

Richard C Lanza

Roberto Accorsi

Kelly E Statham

Harold T Pretorius

A gamma radiation detecting apparatus includes a gamma radiation collimator, a scintillation crystal, a charge coupled device, and an electronic device. The collimator receives and collimates gamma radiation. The scintillation crystal receives the gamma radiation from the gamma radiation collimator and converts the gamma radiation into visible light. The charge coupled device receives the visible light from the scintillation crystal and converts the visible light into an electrical charge. The electronic device converts the electrical charge into a digital image.

Gamma camera system

A variable focus collimator device and method for functional neurological screening. The variable focus collimator uses sets of corresponding holes in two plates of gamma shielding material, arranged so that only gamma rays emitted from a defined focal region detected. If a suitable radio-labeled tracer has been administered to the patient, this may be used to obtain and compare basal and stimulated data from a small number of regions in the brain to diagnose the presence or absence of dementias. The regions of the brain observer are typically about a cm cubed in volume, and their activity is monitored using small doses (&#x3c;2 mCi) of radio-labeled, brain perfusion agents. The regions used are easily and repeatably located relative to well-known anthropological and radiological fiducials. By simply use of symmetry, ratios and cortical to cerebellar comparisons, rapid (&#x2dc;15 minute) screening for dementia may be accomplished.

Apparatus and method for functional neurological screening with adjustable spaced collimator plates

The invention relates to imaging systems that include a coded aperture detection system and an optical detection system. The coded aperture detection system is configured to detect radiation emitted by a radionuclide present within an object and to provide a first detector signal from the detected radiation. The optical detection system is configured to detect optical radiation from the object and to provide a second detector signal from the detected optical radiation. The system also includes a processor configured to prepare first image data from the first detector signal, second image data from the second detector signal, and registered data indicative of a spatial relationship in at least one dimension between the first and second image data. The invention also includes methods of using the new systems, e.g., for sentinel lymph node mapping and tissue resection.

Systems and methods for multimodal imaging using a volumetric representation of an object

Systems and methods for multi-modal imaging having a spatial relationship in three dimensions between first and second image data

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Mount Vernon, OH, United States of America

John D Idoine