The Procter Gamble Company

The Gillette Company

John Christian Haught

William Michael Scheper

Yakang Lin

Steven Hamilton Hoke

Koti Tatachar Sreekrishna

Mark Robert Sivik

Arseni Valerevich Radomyselski

John Christopher Deak

Robb Richard Gardner

Victor Manuel Arredondo

Marc Alan Hester

George Endell Deckner

Arif Ali Baig

Iain Allan Hughes

Sancai Xie

John Cort Severns

Donald James White, Jr

Jeffrey Scott Dupont

Eddy Vos

Jerome Howard Collins

Lowell Alan Sanker

Michael Reilly

Paul Amaat Raymond Gerald France

Joseph Michael Ladd, Jr

Gregory Scot Miracle

Michael E Burns

Keith Homer Baker

Richard Timothy Hartshorn

William Michael Glandorf

Hiroshi Oh

Chanchal Kumar Ghosh

Andre Christian Convents

Jeffrey John Scheibel

Johan Smets

Robert Richard Dykstra

Timothy Woodrow Coffindaffer

Eva Schneiderman

Raphael Warren

David Johnathan Kitko

Andre Cesar Baeck

Christiaan Arthur Jacques Kamiel Thoen

George Douglas Hiler, Ii

Anna Vadimovna Noyes

Sean Michael Renock

Cheryl Sue Tansky

Thomas Glenn Huggins

Qingxin Lei

Brian David Clair

Malgorzata Klukowska

Christian Arthur Jacques K Thoen

Veerle Maria Nathalie Lootvoet

Deepa Ashok Khambe

George Endel Deckner

Dewey Edward Burton

Ashraf Traboulsi

Kenneth Edward Yelm

Michael Jason Ullom

Kotikanyadanam Tatachar Sreekrishna

Carrita Anne Hightower

Gregory Mark Bunke

Benjamin Thomas Circello

Pierig Jean-Marie Lepont

Marcus Anthony Bertin

Scott Edward Powell

Donna Jean Haeggberg

Peter Yau Tak Lin

Robert Leslie Swaine, Jr

Wenzhu Zhao

Graeme Duncan Cruickshank

Christine Marie Cahen

Peter Gerard Gray

Jeffrey Jon Hopkins

Safa Motlagh

Helen Rochelle Kemp

Mark William Glogowski

Cynthia Marie Stark

Katharine Anne Bakes

Sourav Das

Lijuan Li

Michael Duncan

Angela Marie Fieno

Christine Lula Johnson

Arseni Valervich Radomyselski

Pascale Claire Annick Van Steenwinckel

Ellen Louise Colón

Adam Costello

Koti Tatachar Sreekishna

Cathy Renee Schinaman

Kelli Alison Fleisch

Jeffrey John Hopkins

Yogita Vinod Mantri

Donald James White

Steven Hamilton Hoke Ii

Christiaan Arthur Thoen

Michael Eugene Burns

Joseph Michael Ladd

Pascale Claire Van Steenwinckel

Treated surfactant composition containing a water-soluble surfactant and exhibiting improved taste, said composition comprising: a water-soluble surfactant selected from alkyl phosphate surfactants, alkyl phosphate ethoxylated surfactants, betaine surfactants, betaine ethoxylated surfactants, amine oxide surfactants, and mixtures thereof and water; wherein the composition further comprises: less than about 4%, by weight of the water-soluble surfactant, of total undesirable non-polar materials; less than about 2.5%, by weight of the water-soluble surfactant, of alcohols having a carbon chain length of greater than 4; less than about 1%, by weight of the water-soluble surfactant, of amine and amide materials; and less than about 1%, by weight of the water-soluble surfactant, undesirable non-polar materials selected from aldehydes, esters, ketones, and organic acids. Such compositions wherein the compositions have been subjected to liquid-liquid extraction processes.

Water soluble surfactant composition having improved taste

Compositions useful in liquid-liquid extraction processes for improving the taste of water-soluble surfactants, said composition comprising: from about 5% to about 60%, by weight of the composition, of water soluble surfactant; from about 10% to about 90%, by weight of the composition, of water; from about 10% to about 90%, by weight of the composition, of extraction solvent; at least 0.01%, by weight of the composition, of undesirable non-polar materials; wherein the extraction solvent is selected from solvents having individual Hansen solubility parameters of a dispersion force component (&#x3b4;) ranging from about 15 to about 17 (MPa), a polar component (&#x3b4;) ranging from 0 to about 9 (MPa)and a hydrogen bonding component (&#x3b4;) ranging from 0 to about 11 (MPa).

Liquid-liquid extraction composition useful in processing water-soluble surfactants

Methods for detecting and quantifying toxins present in the oral cavity. The methods may include providing a biological sample, providing reporter cells expressing one or more Toll like receptors, exposing the cells to the biological sample, measuring the EC50 value of the lipopolysaccharide on activation of a Toll like receptor, quantification of the lipopolysaccharide in the biological sample.

Detection of oral microbial virulence factors

A method for identifying constituents for detoxifying oral virulence factors and a method for determining the effectiveness of detoxifying agents.

Detoxification of microbial virulence factors in oral cavity

A method for screening compounds and compositions that reduce cetyl pyridinium chloride activation of TRPA1 receptor or TRPV1 receptor.

Reduction in CPC taste aversion by reducing CPC activation of TRPA1, TPRV1, or both

A means of isolating specific stereoisomers and enantiomers from a complex mixture containing a possibility of 32 different stereoconfigurations, thus concentrating the stereoisomer or enantiomer to a high degree of purity.

Method of chromatographic separation

Personal care compositions, such as oral medication compositions containing a flavor system comprising one or more coolants. The pleasant cool sensation provided by a coolant is enhanced in terms of quicker onset, greater intensity, impact or longer duration, which improves appeal and acceptability of the compositions to consumers.

Medications for deposition on biological surfaces

One or more methods for sampling gingival metabolites and biomarkers.

Methods for sampling gingival metabolites

A sucrose polyester composition that imparts a coating providing a slickness to teeth when delivered from an oral care composition.

Compositions for deposition on biological surfaces

Oral care compositions having improved taste, said compositions comprising: a carrier material; from about 0.001 to about 10%, by weight of the composition, of an oral care component selected from metal salts, antimicrobial agents, bad breath reduction agents, bleaching agents, surfactants, or a combination thereof; and from about 0.0001 to about 1%, by weight of the composition, of a TRPA1 agonist selected from vanillin esters; benzoate esters; hydroxybenzoate derivatives; methoxy benzoate derivatives; hydroxybutanedioate derivatives; benzamidobenzoate derivatives; methylpropanoate derivatives; phenyl acetate derivatives; hex-3-enoate derivatives; 2-(furan-2-ylmethylsulfanyl)-3-methylpyrazine; phenylmethoxymethylbenzene; (2R)-2-azaniumyl-3-[(2R)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3E)-2-hydroxy-4,8-dimethylnona-3,7-dienal; (2R)-2-azaniumyl-3-[(2S)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3Z)-3-butylidene-2-benzofuran-1-one; 3-methyl-N-(3-methylbutyl)butan-1-imine; 2-(furan-2-ylmethyldisulfanylmethyl)furan; and combinations thereof. Uses thereof and methods of improving the taste of an oral care composition.

Oral care compositions with improved flavor

Disclosed are personal care compositions for use on hair, skin, oral cavity, throat and other mucosal surfaces containing a flavor/perfume system comprising one or more coolants, wherein the pleasant cool and refreshing sensation provided by the coolant is enhanced in terms of quicker onset, greater intensity or impact and/or longer duration, thereby improving appeal and acceptability of the compositions to consumers. In one embodiment the invention provides oral care compositions comprising

Personal care compositions providing enhanced cooling sensation

TREK-1 agonist comprising composition that reduces perceived oral discomfort sensation and a method for measuring TREK-1 potassium channel activation.

Compositions for delivery of oral comfort sensations

Growing community of inventors

West Chester, OH, United States of America

John Christian Haught