Institute of Organic Chemistry and Biochemistry of the Academy of

Rega Stichting, V.z.w.

Bristol-myers Company

Other

Bristol-myers Squibb Compnay

Gilead Sciences, Inc.

Muzammil M. Mansuri

John C. Martin

Thomas W. Hudyma

Choung U. Kim

Bing Y. Luh

Peter F. Misco

John E., Jr Starrett

Henry G. Howell

Carl E. Fuller

John C Martin

Muzammil M Mansuri

Choung U Kim

Peter F Misco

Joanne J Bronson

Bing Uh Luh

John E Starrett, Jr

Roman Z Sterzycki

Henry G Howell

Carl E Fuller

David R Tortolani

Kuo-Long Yu

Bing Y Luh

Robert W Webb, Ii

Jr Starrett John E

Matthew A Williams

Thomas W Hudyma

Sundaramoorthi Swaminathan

Hongtao Liu

Norbert W Bischofberger

Willard Lew

Louis M Ferrara

Ken Yu

Viral Bhalodia

Robert Peelle

Chris W Chen

Gabriel Gavrielides

Terry Mohn

An apparatus for soaking wood chips or chunks in a liquid and draining the liquid from the wood chips or chunks includes at least a container and a lid. The container includes a sidewall and a bottom surface. The bottom surface and at least a portion of the sidewall are contiguous for containing a liquid therein and for holding the wood chips or chunks within the liquid. The lid has at least one aperture and may be removably coupled to the container. The method places the wood chips or chunks into the apparatus, places all or part of the apparatus into a soaking medium or otherwise fills the apparatus with a soaking medium, soaks the wood chips or chunks, drains the soaking medium from the apparatus, and then positions the wood chips or chunks in a useful position for cooking either with further manipulation or by placement of the entire apparatus in the cooking area.

Method and apparatus for soaking and draining wood chips or chunks

An arrow having an arrowhead assembly attached thereto is provided for marking a remote location with a marking media. The marking media is preferably in the form of a paint ball or a scent ball. The arrowhead assembly includes a media reservoir defining a cavity and a plurality of supports extending outward from the media reservoir along a longitudinal axis. The supports secure the marking media within the cavity in a press-fit connection. In one embodiment, a cap and a resilient nose cone are attached to the media reservoir, surrounding the marking media, to prevent damage to a target upon impacting the target.

Arrow launched media reservoir

An arrow () having an arrowhead assembly () attached thereto is provided for marking a remote location with a marking media (). The marking media () is preferably in the form of a paint ball or a scent ball. The arrowhead assembly () includes a media reservoir () defining a cavity () and a plurality of supports () extending outward from the media reservoir () along a longitudinal axis (L). The supports () secure the marking media () within the cavity () in a press-fit connection. In one embodiment, a cap () and a resilient nose cone () are attached to the media reservoir (), surrounding the marking media (), to prevent damage to a target upon impacting the target.

A reminder device for vehicle key rings or the like includes an integrated processor programmable to provide reminder information in a plurality of operating modes comprising mileage, date, parking location, parking meter expiration, event status and lost key recovery assist.

Automotive accessory reminder device

The present invention is directed to compositions of the formula: ##STR1## wherein: R.sub.2 is H, or an alkyl group having 1 to 3 carbon atoms and 0 to 2 hydroxyls;

Polyhydroxy benzoic acid derivatives and their use as neuraminidase

A series of compounds of Formula I which have anti-tumor activity, and are useful in treating viral infections, their compositions and use. ##STR1## In Formula I B is a purine or pyrimidine base; alk.sub.1 alk.sub.2 and alk.sub.3 are chemical bonds or alkylene groups; Q is hydrogen or hydroxyl; and R.sub.1 -R.sub.4 are hydrogen or alkyl.

Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives

Provided are compounds of the following formulae:

Nucleoside analogs

There are disclosed novel oral prodrugs of phosphonate nucleotide analogs which are hydrolyzable under physiological conditions to yield compounds which are useful as antiviral agents, especially as agents effective against RNA and DNA viruses. They may also find use as antitumor agents.

Prodrugs of phosphonates

Oil change reminder for key rings

A compound of the Formula I or Formula II ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen, hydroxy, chlorine, fluorine, bromine, or an organic substituent having 1 to 5 carbon atoms and selected from acyloxy having a hydrocarbon stem of 1 to 4 carbon atoms, alkoxy, alkylthio, amino, alkylamino and dialkylamino;

Phosphonomethoxy carbocyclic nucleosides and nucleotides

Compounds are provided that generally have the structure BCH.sub.2 CH(R)OCH.sub.2 P(O)(OH).sub.2, wherein B is a purinyl or pyrimidinyl base and R is C.sub.1-2 alkyl substituted with azido or amino, straight or branched alkenyl of 2-6 carbon atoms or alkynyl of 2-6 carbon atoms, together with the monester and diesters of such compounds with a C.sub.1-5 alkanol, and the corresponding salts, hydrates, solvates, the (R) or (S) isomers and the racemic (RS) mixtures thereof. The compounds have desirable antiviral activity.

Antiviral acyclic phosphonomethoxyalkylsubstituted alkenyl and alkynyl

Provided are compounds of the following formulae: A phosphonomethoxymethyoxymethyl purine/pyrimidine derivative of the formula ##STR1## wherein X and X' are the same or different and are hydrogen or alkyl. R and R' are the same or different and are hydrogen, alkyl, hydroxyalkyl or alkanoyl and

Vinyl ethers of nucleoside analogs

Growing community of inventors

Cheshire, CT, United States of America

John C Martin