Scios Inc.

Scios Nova, Inc.

Other

California Biotechnology Inc.

Intrabiotics Pharmaceuticals, Inc.

John C Fiddes

Judith A Abraham

Andrew Asher Protter

Edmund G Tischer

Richard L Mitchell

David J Loury

Conway C Chang

Chee Liang Gu

Deborah A Steinberg

Roger C Fu

De Hwa Chao

The DNA sequences encoding analogs of human acidic and basic fibroblast growth factors (FGF) can be recombinantly expressed to obtain practical amounts of proteins useful in effecting both pathologies related to persistent angiogenesis and wound healing and related tissue repair.

Recombinant fibroblast growth factor analogs

Human basic fibroblast growth factor analog

The present invention provides methods and compositions suitable for treating oral mucositis in animals, including humans, with antimicrobial peptides such as protegrin peptides.

Compositions and methods for the prevention and treatment of oral

The DNA sequences encoding human and bovine acidic and basic fibroblast growth factors (FGF) can be recombinantly expressed to obtain practical amounts of proteins useful in effecting wound healing and related tissue repair.

Recombinant human basic fibroblast growth factor

Disclosed herein are the DNA sequences encoding human and bovine acidic and basic fibroblast growth factors (FGF). Expression of these sequences results in practical amounts of proteins useful in effecting wound healing.

Methods of producing recombinant fibroblast growth factors

DNA encoding human recombinant basic fibroblast growth factor

Isolated DNA sequences, expression vectors and transformant cells are provided which allow for the large scale production of vascular endothelial cell growth factor. The vascular endothelial cell growth factor is useful in the treatment of wounds in which neovascularization or reendothelialization is required for healing.

DNA sequences encoding bVEGF120 and hVEGF121 and methods for the

There is described an isolated vascular endothelial cell growth factor selected from the group consisting of bovine vascular endothelial cell growth factor of 120 amino acids and human vascular endothelial cell growth factor of 121 amino acids. The vascular endothelial cell growth factor is useful in the treatment of wounds in which neovascularization or reendothelialization is required for healing.

Production of vascular endothelial cell growth factor

Growing community of inventors

Palo Alto, CA, United States of America

John C Fiddes