Astrazeneca Ab

Achilles Therapeutics UK Limited

John Briant

Patrick Campbell

Charles Cooke

Christopher Groombridge

William Bakewell

Nicholas Harrison

Orest Lastow

James Daniel John

Nicholas Smartt

Duncan G Young

Samuel Woodhouse

Johan Remmelgas

Simon J Waddelow

Trevor John Penhallurick

Daniel James John

John Trevor Penhallurick

Riccardo Rayan Siena

Toby Joseph Proctor

Joanne Wei-Gnan Tang

Matthew Parker

Michelle Griffin

Medical device

The disclosure relates to a medical dispenser, comprising an outlet and a plurality of sealed compartments containing medicament to be sequentially aligned with and dispensed through said outlet. Movement of an actuator sequentially causes mechanical energy to be built up and then released and converted into an indexing movement of the compartments. The disclosure also relates to an indexing method for a medical dispenser.

Inhaler with indexing linked to movement of cover

The present disclosure relates to a method for entraining in an airflow a medicament powder contained in a cavity having a cavity opening. Large airflow vortices are provided, for instance, by use of an obstacle in a flow passage, The airflow with large vortices is arranged to by-pass the cavity opening, thereby generating an eddy in the cavity which contributes to entraining the powder in said airflow. The present disclosure also relates to a medical dispenser, for instance an inhaler, in which the method may be performed.

Dispenser and method for entraining powder in an airflow

An inhaler including an outlet and a plurality of sealed compartments containing medicament is disclosed. An opening mechanism is provided to open the compartment presently aligned with the outlet. An indexing mechanism sequentially aligns the compartments with the outlet. A latch is provided for latching the opening mechanism in an energized position. The latch cannot latch the opening mechanism before the indexing mechanism has aligned the next compartment with the outlet. A method of priming an inhaler and a method of dispensing a medicament from an inhaler is also disclosed.

Breath activated inhaler

An inhaler, including a base having at least one air-tight, foil-sealed cavity containing medicament is disclosed. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. A method of dispensing a medicament from a sealed cavity inside an inhaler is also disclosed.

Inhalation device and method of dispensing medicament

Growing community of inventors

Hertfordshire, United Kingdom

John Briant