Abbott Point of Care Inc.

John Allister Wood

Cary James Miller

Gordon Bruce Collier

Attila Csaba Nemeth

Jason Andrew MacLeod

William Charles Dicke

Jason Andrew Macleod

Jason Andrew Maclead

The present invention relates to methods for the extraction of nucleic acids from cells, the amplification of segments of nucleic acid and the detection of nucleic acids, all in a convenient and portable manner. In one embodiment, a sample comprising cells containing nucleic acid is exposed to an aqueous mixture comprising a lytic reagent and one or more beads capable of binding the nucleic acid released from said cells to form a nucleic acid-bead complex. The nucleic acid-bead complex is passed through an immiscible liquid layer to separate the nucleic acid from the aqueous mixture. The one or more beads are magnetic, and the nucleic acid-bead complex is passed through and separated from the immiscible liquid layer with an applied magnetic field. The invention is particularly suited for use in point-of-care medical diagnostics testing.

Molecular diagnostics system and methods

The present invention relates to automated devices and methods for the extraction of nucleic acids from cells, the amplification of segments of nucleic acid and the detection of nucleic acids, all in a convenient and portable manner. The invention is particularly suited for use in point-of-care medical diagnostic testing.

The invention relates to a method for the extraction of nucleic acid from cells, the amplification of segments of nucleic acid using modified primers, and the detection of nucleic acids.

Methods of performing nucleic acid amplification assays using modified primers

Nucleic acid separation and amplification

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Kanata, Canada

John Allister Wood