Myrexis, Inc.

Myriad Pharmaceuticals, Inc.

John A Vanecko

Ashok Bajji

Mark B Anderson

Daniel Wettstein

Richard Trovato

Se-Ho Kim

Mark Shenderovich

Rajendra Tangallapally

Benjamin Markovitz

The invention relates to compounds of Formulae I-III: and therapeutic uses thereof, wherein A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carbocyclic group; B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group; R1 is chosen from hydro, alkyl, aryl, heteroaryl, amino, or halo; and L, L, are as defined herein.

Purine-core inhibitors of HSP90 and their use in treating cancer

The invention relates to compounds of Formula I and their therapeutic uses, wherein substituent A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carboxylic group, B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group, R1 is chosen from hydro, alkyl, aryl, heteroaryl amino and halo, and L1 and L2 are as defined in the specification.

Therapeutic compounds and their use in cancer

Growing community of inventors

Thousand Oaks, CA, United States of America

John A Vanecko