Quetzal Biomedical, Inc.

John A Schmidt

William B Rottenberg

John K Prentice

Scott Mathis

An apparatus and method for treatment of congestive heart failure from the right side of the heart. An implantable cardiac stimulation system with a multi-electrode lead having three or more selectable electrodes, together with apparatus for identifying an optimal subset of electrodes, apparatus for shaping a propagating wave front, and apparatus for modifying the intrinsic ventricular cardiac activation sequence, or generating simultaneous or near simultaneous pacing pulses to the septum or right ventricular outflow tract during ventricular systole in order to improve left ventricular cardiac efficiency and reduce mitral regurgitation in patients with dilated cardiomyopathy. A three dimensional map of electrode placement may be calculated. A sub set of the available electrodes in the right side of the heart is selected for stimulation such that septal motion during systole is reduced or the mitral valve area is stiffened to reduce mitral regurgitation.

Multi-electrode apparatus and method for treatment of congestive heart failure

An electrode catheter used in an endocardial procedure to map cardiac electrical activity, heart wall position, heart wall motion and tissue viability. The electrode catheter has a flexible geometric shape for mapping any cardiac chamber and can be rotated within the chamber without being re-deployed. The electrode catheter is made from joining a tube with 4 to 256 wire leads having terminal ends and coiled electrodes. The tube either has holes or a longitudinal slit so that the coiled electrodes can protrude from the central cavity of the tube. The electrode catheter ends with a tip member that is attached to the tube by a swivel connector. The tip member has tines to allow for temporary stability when in contact with a cardiac wall. The electrode catheter is conformed to a flexible shape using a jig and heating process.

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Durango, CO, United States of America

John A Schmidt