Northwestern University

University of Illinois

Washington University

X-celeprint Limited

Tufts College

John A Rogers

Matthew Alexander Meitl

David L Kaplan

Etienne Menard

Fiorenzo G Omenetto

Ralph G Nuzzo

Matthew MacEwan

Heung Cho Ko

Mark Stoykovich

Yonggang Huang

Jongseung Yoon

Jong-Hyun Ahn

Alfred Baca

Matthew Grayson

Michael Motala

Jungil Choi

Yu Yang

Dae-Hyeong Kim

Chang-Jae Yu

In Hwa Jung

Sang-Il Park

Shuai Xu

Tyler R Ray

Wilson Ray

Yi Zhang

Philipp Gutruf

Jonathan A Fan

Anthony R Banks

Siddharth Krishnan

Sheng Xu

Hui Fang

Xinge Yu

Gregory Brown

Zohny S Zohny

Kun Hyuck Lee

Enming Song

Jianing Zhao

Yoon Kyeung Lee

Chulin Wang

Li Gao

Aurelie Hourlier-Fargette

Jungyup Lee

Lin Jia

Rujie Sun

Rak-Hwan Kim

Ha Uk Chung

Richard Chad Webb

Viktor Malyarchuk

Chun-Ju Su

Jonathan T Reeder

Amit B Ayer

Yewang Su

Claire Cecelia Onsager

Yinji Ma

Surabhi R Madhvapathy

Yajing Li

Lauren E Lang

Andreas Tzavelis

Charles M Costakis

Can Cenap Aygen

Jong Yoon Lee

Xinying Wang

Alina Rwei

Yihui Zhang

Provided are apparatuses and methods for non-invasively measuring a blood pressure of a mammal subject. The apparatus includes a first sensor system and a second sensor system time-synchronized to each other and spatially separated by a pulse arrival distance L, and a microcontroller unit (MCU). The first and second sensor systems are respectively attached to first and second positions of the mammal subject for detecting first and second signals. The second position is more distal or proximal to a heart of the mammal subject than the first position. The MCU processes the output signals to determine a pulse arrival time (PAT) as a time delay Δt between detections of the first and second signals, and determines a pulse wave velocity (PWV) based on the PAT and L, where Then the MCU determines the blood pressure P from the PWV, where P is a parabolic function of the PWV.

Apparatus and method for non-invasively measuring blood pressure of mammal subject

Provided herein are flexible, microfluidic epidermal systems and methods useful in the analysis of biofluids for biomarkers corresponding to a variety of conditions and methods of use. The provided systems configured to create conformal contact with the skin to allow for medical testing or screening, either in situ or later external laboratory testing. The described devices and methods may be used for cystic fibrosis screening, glucose monitoring, drug and/or alcohol testing, creatinine monitoring, urea monitoring, pH measurement and dialysis treatment efficacy testing.

Thin, soft, skin-mounted microfluidic networks for detection and analysis of targets of interest in sweat

The disclosed 2-D and 3-D tomographic resistance imaging method improves tomographic resistance image resolution by adopting an orthogonal basis with the maximum number of elements N to describe the maximum resolution resistivity map ρ(r), where this number of elements N is set according to the number of electrodes Q; by defining the orthogonal basis according to any known constraints in the problem, thereby enhancing the resolution where it is needed; by positioning electrodes to be sensitive to these basis functions; and by choosing current I and voltage V contact electrode pairs that maximize signal-to-noise ratio.

High resolution two-dimensional resistance tomography

Provided is a long-term implantable electronic device comprising a first thermally oxidized laver from a first substrate, wherein the first thermally oxidized laver forms a first encapsulation laver; an electronic component supported by the first encapsulation laver, wherein the electronic component and the first encapsulation laver have an exposed surface relative to the first encapsulation laver; a barrier laver that covers the first encapsulation laver and the electronic component exposed surface; a second thermally oxidized layer from a second substrate, wherein the second thermally oxidized layer forms a second encapsulation laver, and the second encapsulation laver is in contact with the barrier layer. Each of the first and second encapsulation layers, the barrier layer, and the electronic component are flexible or bendable, so that the long-term implantable electronic device is configured to conformally contact with a curved biological surface.

Long-term implantable electronic devices

Provided are wireless electronic devices for thermally interfacing with a biological tissue. The device may have a flexible substrate; a thermal actuator supported by said flexible substrate configured to provide a thermal input to said biological tissue; a temperature sensor supported by said flexible substrate configured to measure a temperature to determine thermal conductivity of said biological tissue; and a wireless electronic system in electronic communication with said thermal actuator and said temperature sensor, wherein said wireless electronic system is configured to provide two-way communication with an external controller. Also provided are related methods of using the electronic devices, including for cosmetic, beauty, or medical applications.

Wireless skin sensor with methods and uses

Provided are optical devices and systems fabricated, at least in part, via printing-based assembly and integration of device components. In specific embodiments the present invention provides light emitting systems, light collecting systems, light sensing systems and photovoltaic systems comprising printable semiconductor elements, including large area, high performance macroelectronic devices. Optical systems of the present invention comprise semiconductor elements assembled, organized and/or integrated with other device components via printing techniques that exhibit performance characteristics and functionality comparable to single crystalline semiconductor based devices fabricated using conventional high temperature processing methods. Optical systems of the present invention have device geometries and configurations, such as form factors, component densities, and component positions, accessed by printing that provide a range of useful device functionalities. Optical systems of the present invention include devices and device arrays exhibiting a range of useful physical and mechanical properties including flexibility, shapeability, conformability and stretchablity.

Optical systems fabricated by printing-based assembly

A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power.

Resorbable implant for stimulating tissue, systems including such implant, and methods of using

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Wilmette, IL, United States of America

John A Rogers