Genesys Technologies, Inc.

Roche Nimblegen, Inc.

John A Luckey

Robert L Brumley, Jr

David W Braumann

Patrick J Saunders

Multiplexed microarrays, multiplexed microarray cassettes, and methods for fabricating multiplexed microarrays are disclosed. In some embodiments, the multiplexed microarrays include a substrate, a chamber layer, and at least one channel layer. The topmost channel layer forms a port layer and may be compressible. The multiplexed microarrays may also include a compressible or non-compressible cover or sealing film. The multiplexed microarray cassette includes a base and may also include a cover. The base of the multiplexed microarray cassette includes a plurality of tracks to receive corresponding multiplexed microarrays.

Multiplexed microarray assembly and method for fabricating a multiplexed microarray

An instrument for processing light information to assay chemical or biological molecules is made more flexible by the use of a replaceable filter module. Several light filters, or in one embodiment dichroic mirrors, are mounted in a common module in fixed position relative to each other. The whole filter module can then be removed, and a different one inserted in its place, to change the wavelength bands of light detected by the instrument, as needed, for different applications.

Replaceable filter module

An apparatus for detecting fluorescently-labeled molecules moving in an electrophoretic separation medium. The apparatus utilizes a scanning detection system in which multiple fluorophores are efficiently and simultaneously detected using dichroic mirrors to allow simultaneous detection of fluorescently-labeled molecules in ultrathin gels labeled with several fluorophores and to permit operation at speeds ten times faster than prior art gel separations. The apparatus also utilizes a detection system where lightweight collection optics are in motion while detection optics are fixed in a remote location, thereby allowing exceptionally high-speed scanning.

Growing community of inventors

Merrimac, WI, United States of America

John A Luckey