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The Mead Corporation

Schoeller Technical Papers Company

John A Hill

Qian Shi

Klaus B Kasper

A process for purifying the bacterial fermentation product ivermectin, particularly for use as a reference standard compound in a governmental regulatory approval process. The process includes the use of reversed-phase flash column chromatography coupled with gradient elution. An exemplary eluent mixture includes acetonitrile, methanol and water.

Purification process for anti-parasitic fermentation product

A process is provided for the preparation of a release paper for casting thermoplastic films comprising applying an aqueous coating composition containing an adhesion primer to at least one surface of a paper substrate, and drying the coated substrate. Thereafter, applying a molten film of a low density polyethylene over the coated surface, the molten film of low density polyethylene having an extrusion melt temperature of from about 425.degree. F. to about 575.degree. F., adhering the low density polyethylene film to the coated surface and cooling the low density polyethylene film to a temperature below the melt point of the low density polyethylene. A release paper for casting thermoplastic films is produced comprising a paper substrate and a layer of low density polyethylene adhered to at least one surface of the paper substrate. The polyethylene layer is adhered to the paper substrate by a layer of an adhesion primer. The low density polyethylene has a density of from about 0.917 grams per cubic centimeter to about 0.930 grams per cubic centimeter and the low density polyethylene is applied to the paper substrate at a temperature of from about 425.degree. F. to about 575.degree. F.

Process for producing casting release paper and product

A polyolefin coated photographic base paper having a silk-like textured surface is prepared by extrusion coating the polyethylene on the photographic paper and, while the polyolefin is still plastic, forming the surface of the polyolefin on an engraved chill roll. Pattern depths of 0.4 to 0.7 mils can be produced on the polyolefin surface by this process using polyolefin films as thin as one mil.

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Pulaski, NY, United States of America

John A Hill