Basf Aktiengesellschaft

Johannes Kunze

Dieter Lenke

Josef Gries

Marco Thyes

Hans D Lehmann

Albrecht Franke

Horst Koenig

August Amann

Hubert Giertz

Rolf Lebkuecher

Heinz Georg Vilhuber

6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones of the formula I ##STR1## where R.sup.1 is hydrogen or alkyl of 1 to 3 carbon atoms and R.sup.2, if R.sup.1 is hydrogen, is halogen-substituted alkyl of 3 to 6 carbon atoms or .beta.-haloethyl or, if R.sup.1 is alkyl of 1 to 3 carbon atoms, is halogen-substituted alkyl of 1 to 6 carbon atoms, their manufacture, and therapeutic agents which contain, as the active ingredient, a compound of the formula I, where R.sup.2 may also be halomethyl or .alpha.-haloethyl if R.sup.1 is hydrogen. These compounds may be used as anti-hypertensive agents and for the prophylaxis and therapy of thromboembolic disorders.

6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones and therapeutic agents

2-Aryl-3,4-diaza-bicyclo-[4.1.0]hept-2-en-5-ones, substituted in the phenyl ring, of the general formula ##STR1## their preparation, and therapeutic agents, containing these compounds, which may be used for the treatment of hypertension or of thrombo-embolic disorders.

Novel 3,4-diaza-bicyclo[4.1.0]hept-2-en-5-ones, their preparation, and

3-(P-Biphenylyl)-butyronitrile, its production and its use as an antiphlogistic agent.

3-(P-Biphenylyl)-butyronitrile and therapeutic compositions containing

Growing community of inventors

Triftern, Germany

Johannes Kunze