University of Florida Research Foundation Inc

Iep Pharmaceutical Devices Inc.

Johannes Hugo Van Oostrom

Richard Joel Melker

Samsun Lampotang

Perry Arthur Genova

Akwete Lex Adjei

Michael Joseph Banner

Paul Bradford Blanch

Joachim S Gravenstein

Frederick A Sexton

Anthony A Mancuso

Venkata Meka

Ilona Maria Schmalfuss

A simulated lung for use in real time simulated medical procedures comprising a positive pressure source of a gas, a vacuum pressure source, a fixed interior volume vessel having an inlet, an outlet, and a breath passage port, the inlet in communication with the positive pressure source, and the outlet in communication with the vacuum pressure source, a first flow valve intermediate the positive pressure source and the inlet, a second flow valve intermediate the vacuum pressure source and the outlet, a pressure sensor in communication with the interior volume of the vessel, and means for continuously evaluating a pressure signal generated by the pressure sensor to a desired pressure level within the vessel during the breathing cycle such that a flow of gas entering and exiting the breath passage port of the vessel is synchronized with a predetermined desired flow rate of breathing during the breathing cycle. The desired pressure level depends upon any one of i) a time and event based script, ii) a computer model, iii) or a combination of a time and event based script and a computer model based on a physiological state of a simulated patient.

Lung simulator for an integrated human patient simulator

Disclosure is made of a method employing real-time imaging techniques such as Magnetic Resonance Imaging in order to investigate the effect of air way structures or administration and respiratory drugs when administered by oral inhalation. The information obtained from the practice of this method yields the criteria that can be used, among other things, to design more efficient aerosol drug delivery systems which optimize the amount of medicine delivered to the lung.

Method for improving lung delivery of pharmaceutical aerosols

A method, system, and apparatus for training users in understanding and use of numerous medical devices, including providing for documentation of competency during the training exercise is provided. Preferably, the invention will utilize an &ldquo;interface module&rdquo; (e.g., hand-held device, palm size, laptop, desktop PC, microcontroller, expansion module on a palm/hand-held device) to provide the training interface between the user and the device.

Method, system, and apparatus for medical device training

An open- or closed-loop method and corresponding medical ventilator for providing breathing gas to a patient such that the patient exerts a desired work of breathing during pressure support ventilation, and such that the work of breathing of the patient is monitored and the pressure and/or flow rate of the breathing gas provided to the patient is controlled throughout the inspiratory phase to provide a pressure support ventilation level that provides the desired work of breathing in the patient. The medical ventilator includes at least a pressure sensor and a flow rate sensor, disposed in a functionally open ventilator conduit in fluid communication with the lungs of the patient, electrically coupled to a microprocessor to monitor the average respiratory muscle pressure of the patient and to predict the patient work of breathing as a function of the current value of the average respiratory muscle pressure of the patient, to detect when the patient work of breathing is not within a predetermined work of breathing range, and to generate a response signal thereof. Further, the medical ventilator has a driver circuit electrically coupled to the microprocessor and to an actuator of a pneumatic system which, responsive to the response signal, may adjust the selected pressure support ventilation level of the breathing gas provided to the patient by the ventilator until a pressure support ventilation level is reached such that the patient work of breathing is within the predetermined work of breathing range.

Method and apparatus for controlling a medical ventilator

A method of ventilating a patient comprises initially determining the class of the lungs of a given patient, selecting a pressure or flowrate inspiratory waveform and other ventilatory parameters like inspiratory pause and inspiratory time, among others, appropriate for that lung class, and then ventilating the patient with the selected inspiratory waveform and other ventilatory parameters. New ventilation inspiratory waveforms are provided which have been found to be advantageous for certain lung classes.

Lung classification scheme, a method of lung class identification and

A combination ventilation apparatus and anesthesia delivery system comprises a circulation loop within which oxygen and air or other clinical gas, or a mixture of air, oxygen, nitrous oxide or other clinical gas and anesthetics, are circulated by a variable speed centrifugal blower to a Y-piece which connects the circulation loop to an endotracheal tube or other airway device communicating with a patient. A proportional flow control valve is operative to actively control the pressure or flow at the Y-piece in response to signals from pressure or flow sensors which are positioned to provide measurements representative of the actual pressure and flow conditions within the patient's lungs. Constant circuit volume is maintained by computer control of gas make-up valves in response to the movement of a weighted bellows located between the proportional flow control valve and centrifugal blower.

Ventilation apparatus and anesthesia delivery system

The present invention solves this communication problem by providing a method and apparatus for connecting to and coordinating data communications of various medical devices having different communication protocols. In a preferred embodiment, the invention provides a way to recognize common parameters and separate out only that part of the communication that is different between and specific to the various monitors and therapeutic devices. The invention efficiently utilizes defined common parameters for protocol types and selectively configures the specific settings when required, automatically.

Growing community of inventors

Gainesville, FL, United States of America

Johannes Hugo Van Oostrom