Centre National De La Recherche Scientifique

Institut Pasteur

Institut Pasteur Du Cambodge

Johann Beghain

Benoit Witkowski

Didier Menard

Nimol Khim

Jean-Christophe Barale

Francoise Benoit-Vical

Odile Puijalon

Frederic Ariey

Christiane Bouchier

Frédéric Ariey

Valentine Duru

Benjamin Saint Pierre

Eric Legrand

Françoise Benoit-Vical

A method for genotyping acomprising: (a) providing a sample containing a; and (b) detecting the presence of an increased copy number of the genomic plasmepsin2-3 cluster. A method for the detection of ainfection in a patient comprising: (a) providing a blood sample from a patient and (b) detecting the presence or absence of an increased copy number of the genomic plasmepsin2-3 cluster in the blood sample. Kits for genotyping aand/or detection of ainfection. Methods of treating ainfection.

Methods and reagents for detecting piperaquine-resistant plasmodium falciparum malaria

K13-propeller polymorphism is a useful molecular marker for tracking the emergence and spread of ART-resistant. The invention encompasses methods, compositions, and kits for detecting and genotyping, for example,. The methods, compositions, and kits can be used to detect the presence or absence of a mutated K-13 propeller nucleic acid or protein in the sample.

Molecular marker of plasmodium falciparum artemisinin resistance

Growing community of inventors

Conflans Sainte-Honorine, France

Johann Beghain