Biotage Ab

Ge Healthcare Limited

Other

General Electric Company

Hammersmith Imanet Limited

Johan Ulin

Fredrik Ekdahl

Bengt Langstrom

Per Gunnar Eriksson

Bruce Fletcher Johnson

Irina Velikyan

Peter Henrik Larsen

Martin Orbe

Kent Dahlstrom

Per-Gunnar Eriksson

Maxim Y Kiselev

The present invention relates to a method of obtainingGa from aGe/Ga radioisotope generator and a method of preparingGa-radiolabelled complexes using the obtainedGa. The method comprises elution of the generator with an aqueous chloride ion solution. The invention further relates to an apparatus for carrying out theGa metal complex formation.

[object Object]

A micro vial assembly for performing microwave-assisted chemical reactions on small reaction mixture volumes is disclosed, wherein a reaction vessel () is sealed through a diaphragm () that is capped over an open end of the reaction vessel. The reaction vessel mouths in an end plane of a sleeve () surrounding the reaction vessel, the diaphragm being clamped for sealing the open end of the vessel by means of a cap () which is secured to the sleeve. The sleeve provides a radial extension of the reaction vessel in order to bridge the radial distance between a wall of the reaction vessel and other components in a system for performing microwave-assisted chemical reactions.

Vessel for performing microwave-assisted chemistry on small volumes of reagents

A method of producing [F]Ffrom [F] fluoride through a plasma induced scrambling procedure is provided. The present invention also provides an apparatus for preparing [F]Ffrom [F] fluoride in a plasma induced scrambling procedure. Kit claims for preparing [F]Ffrom [F] fluoride in a plasma induced scrambling procedure as well as method of use and use of claims for preparing [F]Ffrom [F] fluoride through a plasma induced scrambling procedure are also provided.

Vial and tubing therefor

Production of .sup.11 C-methyl iodide

A method is provided for preparing [.sup.18 F]2-fluoro-2-deoxyglucose with an anion exchange resin by effecting an exchange reaction between an aqueous solution of [.sup.18 F]fluoride containing an alkali metal carbonate or bicarbonate, such as sodium bicarbonate, and an anion, such as bicarbonate or carbonate, on the anion exchange resin followed by the displacement reaction with 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-.beta.-D-mannopyranose to form the resulting 2-fluoro-2-deoxyglucose tetraacetate. Improved yields of the [.sup.18 F]2-fluoro-2-deoxyglucose are obtained when the alkali bicarbonate or carbonate is used in the target water.

Method for making 2-fluoro-2-deoxyglucose

Growing community of inventors

Uppsala, Sweden

Johan Ulin