Boehringer Ingelheim Pharma Gmbh & Co Kg

Boehringer Ingelheim Pharma Kg

Boehringer Ingelheim International Gmbh

Ecole Polytechnique Federale De Lausanne

Ingelheim Am Rhein

Airsec S.a.s.

Joerg Schiewe

Bernd Zierenberg

Stephen Terence Dunne

Dieter Hochrainer

Gilbert Wuttke

Horst Wergen

Burkhard Metzger

Georg Boeck

Michael Trunk

Michael Krueger

Paul Bowen

Didier Lancesseur

Jacques Lemaitre

Nathalie Jongen

Cristina Lucica Soare

Marcel Donnet

Jacques Lemaître

Lucica Cristina Soare

The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor

Process for the manufacture of powders of inhalable medicaments

The invention relates to a powder inhaler () with mouthpiece () for dispersing pharmaceutical medicament formulations, which comprises an auxiliary energy source in the form of a pressure medium system (), having a device for supplying () a powder formulation (), while on activation of the pressure medium system a gaseous pressure medium () released by the pressure medium system () forms an aerosol () with the powder formulation () such that the powder particles are present in the gaseous pressure medium () in dispersed form. This is achieved by means of a powder inhaler () comprising a multi-channel nozzle, the channels of which are inclined to one another at an angle such that the aerosol jets flowing through them meet one another downstream behind the nozzle ().

Powder inhaler having a nozzle with a plurality of channels

A dry powder inhaler () is to be made available, with which a particle size and particle size distribution preferred for inhalation are to be achieved and by means of which as high a line particle fraction as possible is to be realized. This is achieved by means of a dry powder inhaler () that is characterized in that provided in the inhaler () is a nozzle () through which the aerosol () flows before leaving the inhaler ().

Dry powder inhaler

The present invention relates to a propellant-gas-free apparatus for the dispensing of liquids, a container cartridge suitable for this for storing the liquid and the ensemble comprising both. The invention comprises a device for the exertion of pressure and for accommodating a container cartridge and a container cartridge in which the dispensing facility is integrated.

Apparatus for the dispensing of liquids, container cartridge suitable for this, and system comprising the apparatus for the dispensing of liquids, and the container cartridge

A method for crystallizing a substance, especially an inhalable medicament, comprising the following steps: Also disclosed is an apparatus for carrying out the method.

Process and apparatus for producing inhalable medicaments

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Mainz, Germany

Joerg Schiewe