Bayer Aktiengesellschaft

Bayer Healthcare LLC

Bayer Intellectual Property Gmbh

Bayer Schering Pharma Ag

Bayer Technology Services Gmbh

Joerg Kauling

Helmut Brod

Andre Pastor

Juri Seletzky

Konstantin Konstantinov

Sebastian Schmidt

Hans-Jürgen Henzler

Klaus Kaiser

Ulrich Steiner

Rolf Treckmann

Erhard Beckers

Jorgen Magnus

Martin Poggel

Cynthia J Galloway

David Naveh

Martin Schiffhauer

Hans-Juergen Henzler

Karsten Sommer

Sonja Danstedt

Arndt Braun

Kathryn Remington

Berthold Boedeker

Peter Commer

Hasso Von Hugo

Franz Schmitt

Kathryn M Remington

Stefan Steigmiller

Hans Tups

The invention relates to the use of single- or multilayer plastic web plates in a sloped channel-type solid material separator with a lamella package.

One-way separator for retaining and recirculating cells

The invention relates to a separator for retaining and recirculating cells in a continuous-flow or batch-flow type plastic bag or bottle, which can preferably be operated outside of a bioreactor. Additionally, the invention relates to a method for retaining and recirculating cells within or outside a bioreactor. The invention further relates to a method for producing the separator according to the invention.

Profiled hollow cylinders attached to a cylinder-shaped body as modules for radiating fluid media with electromagnetic radiation.

Method for producing radiation modules

A method of inactivating microorganisms such as viruses within a fluid such as a biological fluid is disclosed. The method includes the steps of providing a UV reactor, which may take the form of an elongated generally annular reaction chamber surrounding at least one elongated UV lamp, moving the fluid within the reaction chamber in a primary flow directed along the length of the UV lamp, and inducing a circulating secondary flow within the fluid with the secondary flow being superimposed on the primary flow. As the fluid moves through the reaction chamber in the primary flow, it is circulated repeatedly toward and away from the UV lamp in the circulating secondary flow to provide uniform and controllable exposure of the entire volume of fluid to ultraviolet radiation. Microorganisms such as viruses are thus inactivated while desirable components in the fluid, such as proteins, are preserved without the use of a free radical scavenger.

Method of inactivating microorganisms in a fluid using ultraviolet radiation

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Bergisch Gladbach, Germany

Joerg Kauling