Sanofi

Joelle Arnaud

Francis Barth

Serge Martinez

Laurent Hortala

Pascale Roux

Martine Artiaga

The present invention relates to compounds corresponding to formula (I) in which: &#x2014;Rrepresents a substituted phenyl; &#x2014;Rrepresents: &#x2014;a substituted phenyl; &#x2014;a heteroaromatic group, the said group being unsubstituted or substituted one or more times; &#x2014;Rrepresents a group Alk; &#x2014;Rrepresents a hydrogen atom or a (C-C)alkyl; &#x2014;Rrepresents a hydrogen atom, a (C-C)cycloalkyl or a (C-C)alkyl-O-Alk; &#x2014;or alternatively Rand R, together with the nitrogen atom to which they are attached, constitute a heterocyclic radical chosen from: azetidin-1-yl, pyrrolidin-1-yl, piperid-1-yl, morpholin-4-yl; &#x2014;Rrepresents a group &#x2014;COOAlk, a group &#x2014;CONHor a group &#x2014;NHSOAlk; &#x2014;Alk represents a (C-C)alkyl, which is unsubstituted or substituted one or more times with a halogen atom; in the form of the base or of an acid-addition salt. Preparation process and diagnostic and therapeutic use. 

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Paris, France

Joelle Arnaud