Boston Scientific Scimed, Inc.

Cardiac Pacemakers, Inc.

Mayo Foundation for Medical Education and Research

University of Massachusetts

Joel T Eggert

James P Rohl

Douglas Dean Pagoria

Devon N Arnholt

Daniel Shuey

Aaron Abbott

Douglas Pennington

Todd College

Andrew L De Kock

James K Cawthra, Jr

Katherine Lorraine Baldwin

Mark W Boden

Paul E Zarembo

Eric Michael Petersen

Sarah Melissa Gruba

Craig M Wilson

David J Lehse

Benn Horrisberger

Samuel J Asirvatham

David R Wulfman

Daniel J Foster

Mary M Byron

Joseph A Dearani

Brian L Schmidt

James Ryan Mujwid

Joseph T Delaney, Jr

David R Holmes, Iii

Roger W McGowan

Sandra Nagale

Jessica Elizabeth Felton

Arjun D Sharma

Joseph Walker

Troy A Giese

Gurpreet S Sandhu

Ryan Earl Fredrick

Danielle Frankson

Bruce R Forsyth

David A Durand

Gary Pederson

Ronald W Kunkel

Adeniyi O Aremu

Suraj Kapa

Brian J Hanson

Christopher J Koudela

Lance Adam Freeseman

James A Klos

Christopher A Hartemink

Lily Lim

Jonathan P Fettig

Kimberly A Morris

Raymond Gessler

William A Faubion

Mark Kringle

Joseph A Cihlar

Eric J Dozois

David Shreeve

Christopher Macomber

Danilo Decio

Dennis Werner

Tatyana Dyndikova

Jay E Daley

Paul Sorajja

Matthew Hein

Peter M Pollak

Bradley B Rassatt

Andrew J Ro

Scott L Sjoquist

Peter J Wolf

Jeffry Johnson

Katherine Routh

Ken Zhang

Conor O'Sullivan

Diana K Ma

David D Groneberg

James Cawthra

Frank Ryan

Andrew T Marecki

Joshua Haarer

Joseph Edward Adriaens

Sandra L Weeda

Cory P Wright

Richard Lee Tadsen

Poorva Rajguru

Kate Jensen

Brian Kennedy

Jonathan P P Fettig

Mitchell Nelson

Christopher Nguyen

Larry M Killeen

John-Allen O'Brien

Kate Jansen

Dennis B Werner

Joseph J Schachtner

Christopher Perrey

A medical device for cutting a suture during a minimally invasive procedure includes an elongate shaft, a handle housing disposed at the proximal end of the elongate shaft, and a cutting blade disposed proximate the distal end of the elongate shaft. A proximal portion of the handle housing includes an actuation mechanism including a lever arm having a first portion disposed outside of the handle housing and extending distally from the proximal portion of the handle housing. Translation of the first portion of the lever arm relative to the handle housing axially translates the cutting blade within the elongate shaft. A medical device system may include a stand configured to support at least one medical device and a medical device securable to the stand.

Medical device for cutting a suture during a minimally invasive procedure

Devices, systems, and method for adjusting and setting tension of an artificial chordae tendineae. The artificial chordae tendineae is coupleable between a leaflet clip and a tissue anchor. A locking assembly, through which the artificial chordae tendineae extends, is shiftable between a tension-adjusting configuration, in which the artificial chordae tendineae is movable to adjust tension on the leaflet, and a tension-setting or locked configuration, in which the artificial chordae tendineae is inhibited or prevented or locked against moving with respect to the locking assembly to set or fix tension on the leaflet.

Devices, systems, and methods for adjustably tensioning artificial chordae tendineae in a heart

The present disclosure relates generally to the field of medical devices for clamping a leaflet of a heart valve. In particular, the present disclosure relates to medical devices, systems, and methods for delivering artificial chordae tendineae in a patient. In an embodiment, a system may include a clamp having a plurality of arms at a first end. The plurality of arms may have a closed configuration in which the arms are oriented toward each other, and an open configuration in which the arms are oriented away from each other. A spring portion may be coupled to the plurality of arms at a second end that is configured to bias the arms to the closed configuration. The arms of the clamp may be configured to fixedly engage with a leaflet of the heart valve. The second end of the clamp may be configured to couple to an artificial chordae tendineae.

Devices, systems, and methods for clamping a leaflet of a heart valve

A valve fixation device may comprise a unitary elongate member that is biased towards a closed configuration wherein at least a pair of tissue engaging surfaces of the elongate member are held adjacent to each other by a bias force. The bias force is at least equal to a valve leaflet grasping force, enabling the fixation device to grasp and retain leaflets as part of cardiac treatment. A delivery tool including a spreader may independently translate the tissue engaging surfaces to enable cardiac leaflets to be captured and retained by and/or between the tissue engaging surfaces. The valve fixation device may include at least two arms, each of which may be independently controlled to grasp and capture opposing leaflets of a valve, such as the anterior and posterior leaflets of a mitral valve, to reduce the size of the valve opening and improve cardiac performance.

Edge to edge repair device for valves

A medical device may include a plurality of links reciprocally movable between a loose configuration having a first rigidity and a compact configuration having a second rigidity greater than the first rigidity, wherein application of a force to a distalmost link of the plurality of links when the plurality of links are in the loose configuration causes the plurality of links to change orientation relative to one another, and application of the force to the distalmost link when the plurality of links are in the compact configuration does not cause the plurality of links to change orientation relative to one another.

Tissue deflecting devices and related methods of use

Tissue puncture devices, and systems and methods for accessing tissue (e.g., cardiovascular tissue) according to the present disclosure may include a tubular sheath extending along a longitudinal axis, the tubular sheath having a proximal end and a distal end, a needle disposed coaxially in the sheath, the needle having a proximal end and a distal end and being movable along the longitudinal axis of sheath, and a needle control mechanism disposed at the proximal end of the needle, the needle control mechanism being configured to lock the distal end of the needle in a first position retracted within the distal end of the sheath, and release the needle to an unlocked second position such that the distal end of the needle is extendable beyond the distal end of the sheath.

Puncture devices, and systems and methods for accessing tissue

A visualization catheter includes an elongate shaft, a cap portion, and an offset balloon coupled to the distal end of the shaft. The elongate shaft includes a proximal end, a distal end, and a central axis defined therebetween. The cap portion is coupled to the distal end of the shaft. The cap portion also includes a visualization element and defines an aperture. The offset balloon is coupled to the distal end of the shaft and encapsulates the cap portion. The offset balloon defines a center point offset relative to the central axis of the shaft.

Radially-directed balloon visualization device

A catheter configured to dynamically compensate for the impact of internal and external forces that act upon the catheter during use is disclosed. The catheter may include sensors configured to measure received forces on control cables that extend within the catheter. A controller, coupled to the sensors, may record received force measurements associated with a working position of a distal end of the catheter. The controller may monitor subsequently received forces to identify force variances that may deflect the distal end of the catheter from its working position and may apply a driving force to one or more of the control cables to minimize the force variances. Monitoring received forces during use and applying compensating drive forces may reduce deflection of the distal end of the catheter, increasing the accuracy and precision of an annuloplasty procedure while minimizing potential damage to cardiac tissue.

Zero force catheter

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient. In an embodiment, an anchor is movable between a delivery configuration and a deployed configuration, the anchor being in the delivery configuration when disposed within a delivery catheter, the anchor being in the deployed configuration when the anchor is moved beyond a distal end of the delivery catheter. When the anchor is in the delivery configuration it has a first outer dimension and when the anchor is in the deployed configuration it has a second outer dimension, the first outer dimension being smaller than the second outer dimension. The anchor is engageable with a papillary muscle or a heart wall when the anchor is in the deployed configuration and is also coupleable to an artificial chordae tendineae to anchor the artificial chordae tendineae to the papillary muscle or heart wall.

Devices, systems, and methods for anchoring an artificial chordae tendineae to a papillary muscle or heart wall

The present disclosure relates generally to the field of medical devices for treating heart disease. In particular, the present disclosure relates to medical devices, systems, and methods for delivering artificial chordae tendineae in a patient. A system for delivering a chordae tendineae into a heart may include a delivery catheter. A clamp catheter may be configured to translate through the delivery catheter. A spreader may be disposed on the clamp catheter. A first clamp may be at least partially contained in the spreader in a closed configuration and may be attached to the chordae tendineae. An anchor catheter may be configured to translate through the delivery catheter and may have an anchor attached to the chordae tendineae. A sheath may be extended over the anchor catheter and anchor and may be configured to restrain an arm of the anchor.

Devices, systems, and methods for artificial chordae tendineae

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient. A system for adjusting tension in an artificial chordae tendineae includes an artificial chordae tendineae coupleable between a clip and an anchor. The clip is engageable with a leaflet of a heart valve while the anchor is engageable with a papillary muscle or heart wall. The anchor includes a body portion, and a locking portion coupleable with the artificial chordae tendineae and configured to allow movement of the artificial chordae tendineae in a first direction while preventing movement of the artificial chordae tendineae in a second direction opposite the first direction. An actuator is coupled to the locking portion for selectively releasing the locking portion to enable selective movement of the artificial chordae tendineae in the second direction.

Devices, systems, and methods for adjustably tensioning an artificial chordae tendineae between a leaflet and a papillary muscle or heart wall

An implantable medical device includes a first component including a first material, a second component including a second material, and a fiber matrix including a plurality of fibers. The fiber matrix joins the first component to the second component. The fiber matrix includes a first a first portion connected to the first component, and a second portion connected to the second component. The first portion of the fiber matrix is interpenetrated with, and mechanically fixed to, the first material. The first portion of the fiber matrix directly contacts the first material.

Fibrous joinery interface between structures

A method for making an insertable or implantable medical device including a lubricous coating on a silicone substrate includes treating the silicone substrate with an atmospheric plasma at about atmospheric pressure, the atmospheric plasma formed from a noble gas; applying a solution directly to the treated silicone substrate, the solution including a thermoplastic polyurethane; and heating the silicone substrate and the applied solution to form the lubricous coating on the silicone substrate.

Lubricous silicone

Methods and materials related to ostomy devices, and particularly to valves for use with continent ostomies (e.g., ileostomies) are provided herein.

Continent ostomy valve and method of use

Growing community of inventors

Plymouth, MN, United States of America

Joel T Eggert