Centre National De La Recherche Scientifique

Other

Commissariat a L'energie Atomique

Agence Nationale De Valorisation De La Recherche (anvar)

Joel Oiry

Jean-Louis Imbach

Jean-Claude Madelmont

Pascal Clayette

Denise Godeneche

Philippe Fretier

Marie-France Moreau

Jean-Yves Puy

Daniel Parry

Gustin Meyniel

The invention concerns a process for preparing compounds of general formula (I)wherein R and R' represent an alkyl radical or an aryl group; and R&#x2033; is hydrogen or a CO&#x2014;Rgroup wherein Ris an alkyl radical or an aryl group; and wherein these compounds are or not in the thiazolidine form; by protecting the N-acyl-L-cysteine to form an intermediate compound; and then by coupling said intermediate compound with S-acylcysteamine hydrochloride or with thiazolidine.

Antioxidants, preparation processes and their uses

Compounds having the general formula (I), ##STR1## wherein X and Y represent individually H or --NO, at least one of them being a group-NO, n is 0, 1 or 2, R represents hydrogen, an aliphatic, cycloaliphatic, cycloaliphatic-alkyl, aryl or aralkyl radical, or a group of formula, ##STR2## wherein R.sub.1 is a lower alkyl radical or an aryl, all these radicals being optionally substituted. The present invention also relates to the compounds hereabove defined in the form of mixtures of their position isomers. Furthermore, the present invention discloses processes for preparing such compounds, as well as compositions, useful particularly in anticancerous chemotherapy, containing at least one of said compounds as an active principle.

Nitrosoureas compounds preparation thereof and utilization thereof in

A pharmaceutical composition effective in the protection of normal tissues against radiation induced damage comprising administration a compound of the formula

Radioprotective agents having an amino-thioalkyl structure

The invention relates to new chemical compounds. The compounds according to the invention are compounds of the following formula ##STR1## in which one of the substituents A and B is hydrogen and the other is the radical -N.dbd.O. These compounds are suitable for use as medicaments.

Cystamine derivatives suitable for use as medicaments

The invention relates to new chemical compounds. The compounds according to the invention are compounds of the following formula ##STR1## in which one of the substituents A and B is hydrogen and the other is the radical --N.dbd.O. These compounds are suitable for use as medicaments.

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Montpellier, France

Joel Oiry