Gradipore Limited

Gradiant Pty Limited

Joel Margolis

Howard Pericles Manusu

Grace Yim Ngan Chan

Anthony Ellwood

Gel cassette

A cassette for holding an electrophoretic gel. The cassette has two substantially planar wall members formed of a synthetic plastics material, each wall member having two sides and two ends. The wall members are formed integrally along each side with an array of interdigitating ribs and grooves which releasably hold the wall members in substantially parallel array spaced apart sufficiently to define between them an electrophoretic gel receiving space. The ribs and grooves also serve to form a substantially fluid tight seal down each side of the gel receiving space. A plurality of ribs extend between the upper edges of the two wall members to define a series of wells above the gel into which samples to be electrophoretically separated may be placed.

Cassetes for electrophoretic gels

A method and device for the preparative scale recovery of a protein or other charged macromolecule by electrophoretic separation of a mixture of such macromolecules. The device is adapted to be installed between the electrodes of an electrophoretic cell and includes a gel receiving receptacle adapted to hold the end of a gel slab or gel fragments containing an electrophoretically separated macromolecule. An aperture in the base of the receptacle is covered by a first membrane which is substantially permeable to the macromolecules desired to be recovered and a second membrane substantially impermeable to the macromolecules to be recovered but permeable to electrolyte molecules in a buffer solution used in electrophoresis. The two membranes lie in spaced apart array with one another to define therebetween a recovery space. Means are provided to allow the periodic or continuous withdrawal of buffer solution and macromolecules from the recovery space.

Growing community of inventors

Greenwich, Australia

Joel Margolis