Abbott Cardiovascular Systems, Inc.

Joel Harrington

Chad Joseph Abunassar

Rommel Lumauig

Jill A McCoy

Stephen D Pacetti

Kevin Jow

Mark A Ritchie

Ni Ding

Mikael Trollsas

Yung-Ming Chen

David Douglas Hart

Cornel I Ciurea

William Pippey

Ryan Vaughan

Jay A King

James Oberhauser

Syed Faiyaz Ahmed Hossainy

Syed F Hossainy

John E Papp

Michael H Ngo

Dariush Davalian

Diem Uyen Ta

Xiao Ma

Senthil Kumar Eswaran

Mary Beth Kossuth

Fuh-Wei Tang

Richard Rapoza

Annie Liu

Jana Buccola

Jill McCoy

Barbara Stamberg

A scaffold includes a radiopaque marker connected to a strut. The marker is retained within the strut by a head at one or both ends. The marker is attached to the strut by a process that includes forming a rivet from a radiopaque bead and attaching the rivet to the marker including deforming the rivet to enhance resistance to dislodgement during crimping or balloon expansion. The strut has a thickness of about 100 microns.

Scaffolds having a radiopaque marker and methods for attaching a marker to a scaffold

A method of accelerated aging of bioresorbable polymer scaffolds including exposing the scaffold to water is disclosed. The scaffold is exposed to water at a controlled temperature for a selected aging time. The functional outputs, such as radial strength, expandability, and % recoil obtained from aged scaffolds predict those of real-time aging of the scaffold. The accelerated aging factor, which is the required shelf life divided by the aging time, is significantly higher for poly(L-lactide) scaffolds tested than thermal aging.

Accelerated aging for polymeric scaffolds

The present invention involves laser machining polymer substrates to form a stent with laser parameters that minimize damage to the substrate in a surface region adjacent to the machined edge surface. The wavelength and pulse width are selected for this unique application and they can be controlled to minimize the surface modifications (such as voids, cracks which are induced by the laser-material interaction) which contribute to the variation in mechanical properties with distance from the edge surface, bulk mechanical properties, or a combination thereof.

Laser system and processing conditions for manufacturing bioabsorbable stents

Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

Thermal processing of polymer scaffolds

A braided polymeric scaffold, made at least in part from a bioresorbable material is deployed on a catheter that uses a push-pull mechanism to deploy the scaffold. A drug coating is disposed on the scaffold. A plurality of scaffold segments on a catheter is also disclosed.

Braided scaffolds

A polymer scaffold is crimped to a balloon while the polymer material is in a thermodynamically unstable state, or a transient state including crimping shortly after a tube or scaffold processing step that imparts memory to the material, or shortly after rejuvenation of the scaffold.

Crimping polymer scaffolds

A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength.

Short pulse laser machining of polymers enhanced with light absorbers for fabricating medical devices

Methods for attaching a radiopaque marker to a scaffold

An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.

High visibility endoprosthesis and method

Growing community of inventors

Redwood City, CA, United States of America

Joel Harrington