Heartware, Inc.

Joel Graham

Charles Raymond Shambaugh, Jr

Neil Voskoboynikov

Charles R Shambaugh, Jr

A method of implanting a blood pump in a heart of a mammalian subject includes maintaining a temporary plug in an inlet opening of a pump having a pump body and an outlet cannula projecting from the pump body, advancing the pump into a ventricle of the heart through a hole in a wall of the heart so that the inlet of the pump is disposed within the ventricle and the outlet cannula extends through a valve of the heart into an artery, and then withdrawing the temporary plug from the inlet of the pump.

Implantation of a transapical ventricular assist device and kit for same

A ventricular assist device ('VAD') includes a continuous-flow pump () implantable in fluid communication with a ventricle (V) and an artery (A) of a patient to assist blood flow from the ventricle to the artery. The VAD also includes a control circuit () connected to the pump, the control circuit being configured to direct the pump to operate in a series of cycles. Each cycle may include (i) pumping blood at a first speed (RPM) and at a first flow rate during a first period (t); then (ii) decreasing the speed of the pump from the first speed to a second speed (RPM) during a ramp-down period (t); then (iii) pumping blood at the second speed and at a second flow rate during a second period (t); and then (iv) increasing the speed of the pump from the second speed to the first speed during a ramp-up period (t).

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Sunny Isles, FL, United States of America

Joel Graham