Duke University

Quadridox, Inc.

Joel Alter Greenberg

Anuj Jawahar Kapadia

David Brady

Michael E Gehm

Shuo Pang

Kenneth Patrick MacCabe

David Scott Coccarelli

Estimate material coherent scatter form factors for voxels within a scan object by exposing a series of slices of the scan object to an X-ray fan beam within a coherent scatter scanner. Capturing coherent scatter data at a least two X-ray detector modules that are limited to a small-angle field of view by at least one detector-side angle limiting element to provide for capture of small-angle scatter over a wide field of view. Combining the coherent scatter data from the at least two X-ray detector modules to generate an aggregated collection of estimated material coherent scatter form factors for at least some voxels. Combining the aggregated collection of estimated material coherent scatter form factors with a model of aggregate items that clusters voxels in the scan object into model items. Using the aggregated collection of estimated material coherent scatter form factors to estimate a material type for individual model items.

Method for capture of small-angle scatter over wide fields of view

Systems and methods for tissue discrimination are disclosed. The systems and the methods utilize coded x-ray beams. Transmission signals and scatter signals are utilized to determine tissue properties.

Systems and methods for tissue discrimination via multi-modality coded aperture x-ray imaging

An imaging system operative for providing a volumetric molecular image of an object is disclosed. The imaging system interrogates the object with structured x-ray radiation while continuous relative motion between the object and source is induced during a measurement period. As the radiation passes through the object, the radiation scatters based on the molecular composition within the object, and the scattering changes as a function of time due to the relative motion between the source and object. Coherent scatter radiation is detected and processed to reconstruct an estimate of the three-dimensional molecular structure of the object using a reconstruction algorithm, such as maximum likelihood estimation.

Volumetric-molecular-imaging system and method therefor

Growing community of inventors

Durham, NC, United States of America

Joel Alter Greenberg