Musculoskeletal Transplant Foundation

Joed Canales

Eric Semler

Roman Shikhanovich

Alex B Callahan

Anouska Dasgupta

Katrina Carroll

Amy Chang

Michele McAllister

David Wang

Michelle Bubear

Mark Spilker

Roman Shikanovich

Gregory C Fanelli

Helio Marcos Ribeiro

John E Barker

Cesar Chavista

Methods for making surgical implants (or grafts) for the repair of bone defects, and more particularly, surgical implants that include demineralized bone fibers, are disclosed. Also disclosed are methods for increasing the wettability and ensuring uniform density of such implants. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration.

Implants including modified demineralized cortical bone fibers and methods of making same

Modified demineralized cortical bone fibers

The disclosure provides implants containing a plurality of particles containing at least one population of viable cells adherent to and resident in soft tissue matrix or at least one viable population of cells caused to be in contact with the soft tissue matrix; methods of fabricating the implants; and use of the implants in tissue repair.

Tissue-derived tissuegenic implants, and methods of fabricating and using same

Surgical implants (or grafts) for the repair of bone defects, more particularly, surgical implants that include demineralized bone fibers, are disclosed. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration. Methods for making such implants and for increasing their wettability and ensuring uniform density are also disclosed.

The disclosure provides implants containing a plurality of particles containing at least one population of viable osteogenic cells adherent to and resident in an osteoconductive matrix or at least one viable population of osteogenic cells caused to be in contact with the osteoconductive matrix; methods of fabricating the implants; and use of the implants in bone repair. The implant further contains an osteoinductive component. An example of an osteoinductive component is a demineralized bone matrix in the form of particles or fibers.

The invention is directed toward an instrumentation kit used to replace a damaged human knee joint meniscus with an allograft meniscus implant. The kit includes a workstation having a base and upright end sections with a clamping assembly is mounted on the end sections and a movable cutting guide mounted to a side wall of each end section. The tibia is then drilled with a drill to a desired depth and length and a groove is formed in the tibia with an osteotome so that the width is the same as the width of the bone base of the meniscus implant which has been trimmed in the workstation.

Instrumentation for repair of meniscus tissue

Growing community of inventors

Harrison, NJ, United States of America

Joed Canales