Johnson and Johnson Vision Care, Inc.

Johnson & Johnson Vision Products Inc.

Joe M Wood

Douglas G Vanderlaan

Michael Francis Widman

David Curtis Turner

Charles W Scales

Peter W Sites

Brian Aitken

James D Ford

Ture Kindt-Larsen

John B Enns

Christopher Wildsmith

P Mark Powell

Mukul Kanaujia

Azaam Alli

Frank F Molock, Jr

Gregory A Hill

Robert B Steffen

Ivan M Nunez

John C Heaton

Ann-Marie Wong Meyers

Robert N Love

Lenora L Copper

Paul Mark Powell

James S Jen

Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crosslinked substrate network such that the grafting composition polymerizes with the crosslinked substrate network at the selective regions.

Ophthalmic devices containing localized grafted networks and processes for their preparation and use

An apparatus and method for forming a contact lens includes submerging a convex optical quality surface of a forming optic in a reservoir containing Lens Reactive Mixture, projecting a first Actinic Radiation with a first wavelength through pre-selected regions of the forming optic that correspond to increased thickness in the lens to be formed for selectively polymerize the Lens Reactive Mixture on a Voxel by Voxel basis; projecting a second Actinic Radiation with a different wavelength through the entire forming optic to selectively polymerize the Lens Reactive Mixture on a Voxel by Voxel basis, removing the forming optic and polymerized Lens Reactive Mixture from the reservoir and applying a Fixing Radiation to form the contact lens.

Multiple-wavelength lens forming system and method

A Free-form contact lens and method of making the same. The lens includes a posterior optical quality surface having a concave shape, an opposing anterior surface having a convex shape both of which join at a lens edge that defines an outer periphery of the contact lens, and at least a first lens feature having a predetermined shape and made of a first polymerized Reactive Mixture. The remainder of the lens is made of a second polymerized Reactive Mixture that is different than the first polymerized Reactive Mixture, and that is covalently bonded thereto.

Methods for incorporating lens features and lenses having such features

This invention discloses apparatus for processing one or more of a Lens Precursor, a Lens Precursor Form and an ophthalmic Lens. The apparatus provides for vapor phase processing of the subject Lens Precursor, a Lens Precursor Form and an ophthalmic Lens.

Apparatus for vapor phase processing ophthalmic devices

Biomedical devices with stable, hydrophilic and antimicrobial coatings are provided. The coatings are formed using a coupling agent to bond a carboxyl containing hydrophilic coating to the surface by ester or amide linkages.

Biomedical devices with hydrophilic coatings

The invention provides biomedical devices. In particular, the invention provides biomedical devices on the surfaces of which stable, hydrophilic, amide-containing coatings are formed.

Biomedical devices with amid-containing coatings

The invention is a method of making a coated contact lens with desirable physiological performance. Preferably, the lenses are made from hydrophobic contact lens substrate with a hydrophilic coating material. The hydrophobic lens substrate is coated with a hydrophilic material having an expansion factor greater than one. The coated lenses have low physical defect and surface roughness profiles.

Contact lens coating selection and manufacturing process

Acylphosphine initiators used in making ophthalmic lenses are stabilized by the addition of an acid to the monomer mix used to make the lenses.

Stable initiator system

A highly purified monomer-dye unit is disclosed. A method for producing a highly purified monomer-dye unit is also disclosed. A hydrophilic monomer is reacted with a halotriazine or vinyl sulfone dye in the presence of a base under conditions that yield highly pure monomer-dye units.

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Jacksonville, FL, United States of America

Joe M Wood