Bioagency Ag

Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v.

Universiteit Gent

Jochen Wiesner

Hassan Jomaa

Boran Altincicek

Martin Hintz

Ann-Kristin Kollas

Armin Reichenberg

Oliver Wolf

Andreas Vilcinskas

Serge Van Calenbergh

Matthias Eberl

Mathias Eberl

Timothy Haemers

Vincent Devreux

Anne-Kathrin Poeppel

Anne-Kathrin PÖPPEL

The present invention discloses polypeptides comprising an amino acid sequence being identical with at least 12 contiguous amino acid residues of SEQ ID No 2. The polypeptides according to the invention are effective against fungi, especially against fungi causing plant diseases, and against fungi colonizing agricultural products. The invention further discloses processes for preparing such polypeptides, and nucleic acids coding for such polypeptides. In addition, the invention relates to processes and preparations for treating plants using the polypeptides according to the invention, and to the use of the nucleic acids according to the invention for producing crops that are protected against damage from fungi.

Polypeptides against plant pathogenic fungi

The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.

Organophosphorous compounds for the activation of gamma/delta T cells

The present invention relates to novel phosphonic acid compounds having the structural formula (I): wherein: (a) R is a group of 1 to 5 substituents independently selected from the group consisting of fluoro, chloro, bromo, Calkoxy, Calkyl, hydroxy, formyl, trifluoromethoxy, phenyl, heterocyclic, heterocyclic-substituted methyl, aminomethyl, hydroxy methyl, bromomethyl, sulfonyl chloride, acetyl chloride, nitroso and cyano, (b) Ris selected from the group consisting of hydrogen, Calkyl, Ccycloalkyl, aryl, arylalkyl and heterocyclic, and (c) Ris selected from the group consisting of hydroxy and hydroxy-protecting groups, and stereoisomer, solvates and salts thereof. These compounds are useful as anti-infectious and anti-parasitic agents, in particular anti-malaria agents.

Organophosphoric derivatives useful as anti-parasitic agents

Organo-phosphorous compounds for activating gamma/delta T cells

Growing community of inventors

Giessen, Germany

Jochen Wiesner