Nanogen Recognomics Gmbh

Jochen Müller-Ibeler

Norbert Windhab

Stefan Kienle

Markus Schweitzer

John R Havens

Thomas J Onofrey

Charles Greef

Daguang Wang

Christoph Brücher

Stefan Raddatz

Jill Orwick

Richard Anderson

This invention relates to attachment chemistries for binding macromolecules to a substrate surface or to other conjugation targets. More particularly, this invention relates to attachment chemistries involving branched or linear structures having one or more hydrazide attachment moieties for binding the macromolecules to a substrate surface, or for other conjugation reactions. Novel modifying reagents are provided for the introduction of protected hydrazide attachment moieties or precursor forms of such hydrazides to the macromolecule, either as a single hydrazide or as multiple hydrazides.

Hydrazide building blocks and hydrazide modified biomolecules

Growing community of inventors

Diez, Germany

Jochen Müller-Ibeler