Basf Se Corporation

Joanna Martyna Krawczyk

Oskar Zelder

Stefan Haefner

Hartwig Schröder

Esther Dantas Costa

Gregory Von Abendroth

Christoph Wittmann

Judith Becker

René Stellmacher

Hartwig Schroeder

Thomas J Lyons

Anna Lange

Ewa Hughes

Eudes De Crecy

Benjamin J Lyons

Torsten Renz

Christian Riedele

Hartwig SCHRÖDER

The present invention relates to a process for producing an organic acid by fermentation, comprising the process steps: I) cultivating microorganisms in a culture medium to which are fed, as assimilable carbon sources, glycerol and a further carbonaceous compound, to allow the microorganisms to produce the organic acid, thereby obtaining a fermentation broth comprising the organic acid; II) recovering the organic acid or the salt thereof from the fermentation broth obtained in process step I); wherein, at least for a certain period of time in process step I), the consumption rate of the further carbonaceous compound (Cin g per liter per hour) is lower than the maximum theoretical consumption rate of the further carbonaceous compound (CRin g per liter per hour).

Use of glycerol with limited feed of carbohydrates for fermentation

The present invention relates to a modified microorganism having, compared to its wildtype, &#x2014;a reduced activity of an enzyme encoded by the ptsA-gene, &#x2014;a reduced activity of an enzyme encoded by the ptsH-gene or &#x2014;a reduced activity of an enzyme encoded by the ptsA-gene and a reduced activity of an enzyme encoded by the ptsH-gene, wherein the wildtype from which the modified microorganism has been derived belongs to the family of Pasteurellaceae. The present invention also relates to a method for producing succinic acid and to the use of modified microorganisms.

Genetically modified microorganism for improved production of fine chemicals on sucrose

The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the pykA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.

Microorganisms for succinic acid production

The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the wcaJ-gene. The present invention also relates to a method for producing an organic compound and to the use of a modified microorganism.

Modified microorganism with improved biomass separation behaviour

The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the fruA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.

Modified microorganism for improved production of fine chemicals on sucrose

Growing community of inventors

Mannheim, Germany

Joanna Martyna Krawczyk