Numat Biomedical, S. L.

Laboratories Sanifit, S. L.

Numat Medtech, S.l.

Joana María Ramis Morey

Marta Monjo Cabrer

Bernat Isern Amengual

Fernando Tur Espinosa

Joan Perelló Bestard

Alba Córdoba Insensé

María Del Mar Arriero Sánchez

Eva Martín Becerra

Rubén Henríquez Paláez

María Satué Sahún

Manuel Gómez Florit

María Del Mar Arriero SÁNCHEZ

The present invention provides a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein an antioxidant compound selected from the group of flavonoids or methoxytryptophols, an ester thereof, a pharmaceutically acceptable salt thereof or a combination thereof, is/are coated to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. This implant is useful for replace bone tissue in vertebrate animals, and furthermore restore the normal function of said tissue, mainly due to its ability of induce osseointegration and soft tissue attachment.

Implants for inducing soft and hard tissue integration

The present invention relates to a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein a compound selected from the group consisting of an IP, an ester of an IP, and/or a pharmaceutically acceptable salt thereof, or a combination thereof, is/are covalently bound to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. The covalent bond between the IP and the metal, metal alloy or metal oxide surface can be further assisted by the use of a linker. An implant according to the invention provides for a modulated and/or improved osseointegrative effect when implanted into a body, such as a mammalian body, by virtue of the coating comprising covalently bound phytate.

Biocompatible implant

Growing community of inventors

Palma De Mallorca, Spain

Joana María Ramis Morey