The Proctor 'Gamble Company

Norwich Eaton Pharmaceuticals, Inc.

Joan B Szkutak

Leane Kristine Davis

Gerald B Kasting

Ronald L Smith

Eugene G Drust

Robert S Kiner

Eric J Holden

A resilient squeeze bottle dispensing package including an internal flexible bag which is suitable for dispensing viscous product such as toothpaste, but which includes an air valve which will automatically permit pressure equilibration in the chamber formed between the flexible bag and the interior of the bottle in response to a decrease in the atmospheric pressure surrounding the package. Employing a valve which permits such automatic pressure equilibration avoids unwanted oozing of viscous product from the discharge orifice of the package when the atmospheric pressure surrounding the package decreases, e.g., as by airplane travel or by travelling from a first elevation to a second substantially higher elevation.

Resilient squeeze bottle employing air check valve which permits

Compositions for the transdermal delivery of buprenorphine comprising a safe and effective amount of buprenorphine in a carrier comprising:

Compositions for the transdermal delivery of pharmaceutical actives

Growing community of inventors

West Chester, OH, United States of America

Joan B Szkutak