Bayer Aktiengesellschaft

Lanxess Deutschland Gmbh

Bayeraktiengesellschaft

Joachim Komoschinski

Helmut Fiege

Guido Steffan

Walter Lange

Reinhold Gehring

Markus Eckert

Michael Dockner

Hans-Josef Buysch

Ernst Kysela

Herbert Diehl

Klaus-Christian Paetz

Bernhard Beitzke

Bernd Griehsel

Volker Glock

Polyhalogenated cinnamic acids and cinnamic acid derivatives are prepared by reacting diazonium salts accessible from polyhalogenated anilines with acrylic acid or acrylic acid derivatives in the presence of a homogeneous, palladium-containing catalyst at about &#x2212;5 to about +100&#xb0; C. Some of the cinnamic acids and cinnamic acid derivatives obtainable in this way are new. Cinnamic acids and cinnamic acid derivatives which can be prepared according to the invention can be used for the preparation of indanones which are precursors for agro- and pharmaceutical chemicals and for substances having liquid-crystalline properties.

Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives

The present invention describes a process for preparing 4-amino-1-naphthol ethers which is characterized in that naphthol ethers are first prepared from 1-naphthols, the former are then converted to the corresponding 4-acetamino-1-naphthol ethers and then the acyl group is cleaved off, and further describes 4-acetamino-1-naphthol ethers obtained thereby.

Preparation of 4-amino-1-naphthol ethers

The invention relates to substituted cinnamic acids and cinnamic acid esters of formula (I), wherein X represents F, Cl or J and R and R are the same or different and represent hydrogen, an optionally substituted C -C -alkyl radical or an optionally substituted benzyl radical. Substituted indanone carboxylic acid esters are produced using said substituted cinnamic acid and cinnamic acid ester in a technically simple and non-dangerous manner as far as safety is concerned.

Substituted cinnamic acids and cinnamic acid esters

2-Halogenoindan-1-ones are prepared in an advantageous manner by converting anilines into diazonium salts and these, with acrylic compounds, into 3-phenyl-1-halogenoproprionic acid derivatives, and latter are cyclized.

Process for preparing 2-halogenated indan-1-ones

In a particularly advantageous process for producing 2-cyanoindan-1-ones from 2-halogenated indan-1-ones by reaction with a cyanide salt, the cyanide salt is dissolved in a dipolar aprotic solvent or in a water-miscible ether and 2-halogenated indan-1-one is metered into this solution.

Process for preparing 2-cyanoindan-1-ones

A process for producing a compound of the formula (I) ##STR1## wherein Hal is chlorine or bromine, and R.sup.1 to R.sup.5 are, each independently, hydrogen, unsubstituted or substituted C.sub.1 -C.sub.10 -alkyl, or unsubstituted or substituted C.sub.6 -C.sub.10 -aryl;

Process for the preparation of halogenomethylcyclopropanes and ultrapure

The invention relates to a process for the preparation of halogenomethylcyclopropanes.

Process for the production of halogen methyl cyclopropanes and highly

N-aryl-N'-alkyl-piperazines are obtained in a particularly simple manner, in good yields and in short reaction times when an aniline is reacted under pressure with an N-alkyl-bishydroxyethyl-amine in the presence of a strong acid.

Process for preparing N-aryl-N'-alkyl-piperazines

Optionally substituted ODOP is obtained by reaction of optionally substituted o-phenylphenol with PCl.sub.3 in the presence of Lewis acids at elevated temperature in a first stage, with according to the invention an excess of at least 0.05 mol of PCl.sub.3 per mol of o-phenylphenol being maintained during the entire reaction time, and, after removal of the PCl.sub.3, by hydrolysis in a second stage using 1-2 mol of H.sub.2 O per chlorine equivalent of the product of the first stage at 50.degree.-150.degree. C. and with removal of HCl and residual H.sub.2 O.

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Kö'ln, Germany

Joachim Komoschinski