Boehringer Ingelheim Gmbh

Dr. Karl Thomae Gmbh

Dr. Karl Thomae Gesellschaft MIT Beschranter Haftung

Joachim Kahling

Rudolf Hurnaus

Gerhart Griss

Wolfhard Engel

Gunter Trummlitz

Wolfgang Grell

Robert Sauter

Eckhard Rupprecht

Bernhard Eisele

Nikolaus Kaubisch

Manfred Kleemann

Wolfgang Eberlein

Volkhard Austel

Helmut Pieper

Joachim Heider

Peter Danneberg

Klaus Reinhold Noll

Ernst Seeger

Johannes Keck

Gerd Kruger

Eckhart Bauer

Eberhard Kutter

Harald Ziegler

Helmut Ballhause

There are described novel carboxylic acid derivatives of the formula ##STR1## and derivatives of the formula ##STR2## and the addition salts thereof, which exhibit an effect on the intermediary metabolism. Furthermore, the compounds of Formula Ia as well as the compounds of Formula I possess blood-sugar lowering properties.

Carboxylic acid amides and pharmaceutical compositions containing them

Compounds of the formula ##STR1## wherein R.sub.1 is phenyl, halo- and/or methyl-substituted phenyl or pyridinyl;

Vinylogous carboxamides

This invention relates to novel indole derivatives of formula ##STR1## and the non-toxic, pharmacologically acceptable salts thereof. These compounds exhibit desirable pharmacological properties, especially lipid-level lowering and anti-atherosclerotic activity. The compounds of the invention may be prepared by, for example, alkylation of a corresponding hydroxy indole.

2[3-(4-Chlorophenyl)-1,2-dimethyl-1H-indol-5-yloxy]-2-methyl propanoic

Compounds of the formula ##STR1## wherein Ar is phenyl; mono- or di-substituted phenyl, where the substituents are one to two halogens, one to two alkyls of 1 to 3 carbon atoms, or one amino, nitro, cyano or trifluoromethyl; or pyridinyl;

2-[(Amino)-aryl-methylene]-benzo[b]thiophen-3(2H)-ones

Compounds of the formula ##STR1## wherein A is lower alkylene,

Sulfur-containing derivatives of

Compounds of the formula ##STR1## wherein (A) WHEN THE AMINO-SUBSTITUENT IS IN THE P-POSITION WITH RESPECT TO THE CARBONYL GROUP,

Amino-benzoic acid amides

Pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula ##SPC1## Wherein

Pharmaceutical compositions containing a 1-phenyl-2,2,4,4-C.sub.1

This invention relates to cyclobutane derivatives having the formula ##SPC1## Wherein R.sub.1 to R.sub.3, which may be the same or different, represent hydrogen atoms, halogen atoms, hydroxy, trifluoromethyl, benzyloxy, acyloxy groups, alkyl groups with 1 to 6 carbon atoms, alkoxy groups with 1 to 3 carbon atoms, phenyl, cyclohexyl, or 2 of the radicals R.sub.1 to R.sub.3 together represents a methylenedioxy group,

1-Phenyl-2,2,4,4-C.sub.1 -C.sub.2 alkyl-3-[4-(phenyl or

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Biberach, Germany

Joachim Kahling