Autodisplay Biotech Gmbh

Henkel Ag & Company, Kgaa

Joachim Jose

Thomas Weber

Andreas Taden

Roland Breves

Irmgard Schmidt

Jae-Chul Pyun

Birgit Veith

Shanna Sichwart

Iasson Tozakidis

Claudia Reicheneder

Mark George Teese

The present invention relates to a method for the surface display of a recombinant polypeptide on the surface of a host cell, said method comprising the steps: (a) providing a host cell transformed with a nucleic acid fusion operatively linked with an expression control sequence, said nucleic acid fusion comprising: (i) a portion encoding a signal peptide, (ii) a portion encoding the recombinant polypeptide to be displayed, (iii) a portion encoding a transmembrane linker, and (iv) a portion encoding the trans porter domain of an EhaA protein, and (b) culturing the host cell under conditions wherein the nucleic acid fusion is expressed and the expression product comprising the recombinant polypeptide is displayed on the surface of the host cell.

Surface display of functional proteins in a broad range of gram negative bacteria

The present invention relates to peptides, in particular dodecapeptide-containing coating agents, adhesion promoters or adhesives for oxidic surfaces, a multilayer composite or a coated substrate, containing compounds which are formed entirely or in part of dodecapeptides as adhesion promoters between at least two adjacent layers of the composite or between the coating and the substrate, and to dodecapeptides that can be used as coating agents, adhesion promoters or adhesives for oxidic surfaces.

Peptides that can be used in coating agents, adhesion promoters or adhesives for oxidic surfaces

The present invention refers to a method for binding a recombinant polypeptide to a carrier, wherein a layer is bound to a carrier, and the layer comprises a recombinant polypeptide on the surface distal to the carrier.

Method for binding a recombinant polypeptide to a carrier

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Duesseldorf, Germany

Joachim Jose