Basf Se Corporation

Basf Aktiengesellschaft

Basf Agro B.v.

Dow Agrosciences LLC

Basf Aktiengeseschaft

Joachim Gebhardt

Michael Rack

Michael Keil

Bernd Wolf

Wolfgang Von Deyn

Ernst Baumann

Rene Lochtman

Uwe Josef Vogelbacher

Roland Goetz

Joachim Rheinheimer

Matthias Witschel

Helmut Hagen

Guido Mayer

Maximilian Dochnahl

Volker Maywald

Norbert Götz

Norbert G&ouml;tz

Timo Frassetto

Thomas Schmidt

Frederik Menges

Ulf Misslitz

Helmut Zech

Jan Hendrik Wevers

David Cortes

Rodney F Klima

Stefan Benson

Manfred Ehresmann

Sandra Löhr

Peter Schaefer

Heinz Isak

Heidi Emilia Saxell

Jochen Schroeder

Florian Vogt

Wen Xu

Martin Viertelhaus

Jochen Schröder

Axel Pleschke

Hartmann Konig

Christopher Koradin

Steffen Kudis

Heinz Friedrich Sutoris

Ulf Miβlitz

Gerhard Hamprecht

Robert Leicht

Uwe Kardorff

Jan Klaas Lohmann

Helmut Kraus

Regina Luise Hill

Karl-Otto Westphalen

Helmut Walter

Martina Otten

Thomas Zierke

Stefan Engel

Peter Erk

Peter Sch&auml;fer

Sandra Loehr

Cyrill Zagar

Bernd Sievernich

Robert Reinhard

Norbert Gotz

Werner Seitz

Sebastian Soergel

Hagen Jaedicke

Gerhard Cox

Daniel Saelinger

Tiziana Chiodo

Birgit Gockel

Jens Renner

Roland Götz

Alfred Michel

Eberhard Ammermann

Gisela Lorenz

Hubert Sauter

Norbert Goetz

Karl Eicken

Gary A Roth

Reiner Kober

Bernd Muller

Matthias Bratz

Oliver Wagner

Rainer Seele

Harald Rang

Jochen Dietz

Henricus Maria Martinus Bastiaans

Bernhard Zipperer

Christopher Thomas Hamilton

Eric George Klauber

Thomas Kröhl

David Bruce Gorman

Stefan Orsten

Michael Gullo

Michael Allen Gonzalez

Harish Shinde

Thomas Kroehl

Roland Gotz

Kailaskumar Borate

Peter Sch{umlaut Over (a)}fer

Rudolf Haeberle

Stefan Fülster

Stefan Fuelster

The present invention relates to a process for the preparation of substituted 4-(N′-hydroxy-carbamimidoyl)benzoic acids, which can be obtained by nitrilase catalyzed hydration of substituted terephthalonitriles of formula (II) in an aqueous medium to afford (ammonium) 4-cyanobenzoic acids (IIa). The hydration is followed by treatment of the aqueous reaction medium with hydroxylamine or a salt thereof to afford amidoximes (I).

Preparation of substituted 4-(N'-hydroxycarbamimidoyl)benzoic acids

The present invention relates to a novel crystalline form of 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide recently assigned the common name dimpropyridaz. The invention also relates to the use of the crystalline form B for combating invertebrate pests and to formulations for plant protection which contain the crystalline form B of 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide. The crystalline form B according to the present invention can be identified by powder X-ray diffractometry on the basis of its powder X-ray diffraction diagram, hereinafter also termed powder X-ray diffraction pattern or PXRD pattern, of the polymorph form B recorded using Cu—Kα radiation (1.54178 Å) at 25° C. displays the 3 following reflections, quoted as 2θ values: 20.69±0.10°, 24.15±0.10° and 30.52±0.10°. In addition to these 3 reflections, the polymorph B of the present invention may display in such a PXRD pattern one or more, in particular at least 2, often at least 4, in particular at least 6 or at least 8 reflections and especially all of the reflections quoted hereinafter as 2θ values: 7.99±0.10°, 10.07±0.10°, 12.38±0.10°, 15.31±0.10°, 15.97±0.10°, 16.50±0.10°, 18.03±0.10°, 19.29±0.10°, 20.22±0.0.10°, 20.96±0.10°, 23.40±0.10°, 23.70±0.10°, 26.09±0.10°, 27.26±0.10° and 32.91±0.10°.

Crystalline forms of 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide

The invention relates to an aqueous pesticidal composition comprising a) suspended particles comprising dimpropyridaz, and b) triethylammonium chloride. It also relates to a method for producing the pesticidal composition; to a method for treating plant propagation material; to the use of triethylammonium chloride for inhibiting the crystal growth of particles of dimpropyridaz that are suspended in an pesticidal composition; a method for treating or protecting an animal from infestation or infection by invertebrate pests which comprises bringing the animal in contact with a pesticidally effective amount of the pesticidal composition; to a method for combating or controlling invertebrate pests, which method comprises contacting said pest or its food supply, habitat or breeding grounds with a pesticidally effective amount of the pesticidal composition; and to a method for protecting growing plants from attack or infestation by invertebrate pests, which method comprises contacting a plant, or soil or water in which the plant is growing, with a pesticidally effective amount of the pesticidal composition.

Stabilization of dimpropyridaz suspensions by triethylammonium chloride

The present invention relates to a method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol in high purity. Especially it relates to a method in which this compound is effectively separated from its 1,2,4-triazol-4-yl isomer.

Method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol

This invention relates to a process for the epoxidation of a tetrasubstituted alkene such as terpinolene to the corresponding epoxide such as terpinolene epoxide by reacting the tetrasubstituted alkene with performic acid prepared in situ from formic acid and hydrogen peroxide in the presence of at least one buffering agent. Further, the invention relates to the use of an oxidizing agent comprising hydrogen peroxide and formic acid for the in-situ epoxidation of a tetrasubstituted alkene.

Process for the epoxidation of a tetrasubstituted alkene

The present invention relates to a process for the preparation of the compounds II from the respective oxo compounds. Furthermore, the invention relates to a process for the preparation of triazole compounds from oxiranes II.

Process for the preparation of substituted oxiranes and triazoles

The present invention relates to a process for the purification of pyrazolpyridazines of formula I wherein the variables are as defined in the specification, by adding HCl to a solution of the pyrazolpyridazine in an inert solvent under non-aqueous conditions, effecting crystallization of the HCl-salt, isolating the resulting precipitate.

Process for purification of pyrazolpyridazines

The present invention relates to a process for the preparation of the compounds of formula II using a lanthanoid salt.

Process for the preparation of substituted phenoxyphenyl alcohols

This invention relates to a process for preparing (&#xb1;)-2-exo-(2-Methylbenzyloxy)-1-methyl-4-iso-propyl-7-oxabicyclo[2.2.1]heptane of the formula (I), (I) any one of its individual enantiomers or any non-racemic mixture thereof comprising the steps of (a) deprotonating (&#xb1;)-2-exo-hydroxy-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane of the formula (II), (II) any one of its individual enantiomers or any non-racemic mixture thereof in the presence of at least one base of the formula [Mm+]n [An-]m (III) wherein Mm+ represents a m-valent metal cation wherein m is an integer of 1 or 2, and An_ represents a n-valent anion wherein n is an integer of 1 or 2, said base being capable of forming a solvent S1 selected from water, a C1-C4 alkyl alcohol or any combination thereof under the reaction conditions, to form a metal alkoxide or metal alkoxide solvate of the formula (IV), (IV) any one of its individual enantiomers or any non-racemic mixture thereof wherein M, m and the solvent S1 have the same meaning as defined for the base of formula (III), and x denotes a number from 0 to 10, and (b) reacting the metal alkoxide or metal alkoxide solvate of the formula (IV), any of its individual enantiomers or any non-racemic mixture thereof with a 2-Methylbenzyl compound of the formula (V), (V) wherein X is a leaving group, wherein the steps (a) and (b) are conducted in the presence of at least one inert organic solvent S2 and comprise a further step of (c) simultaneously removing the solvent S1 from the reaction mixture. 

Process for preparing 2-exo-(2-methylbenzyloxy)-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane

This invention relates to a process for preparing (&#xb1;)-2-exo-(2-Methylbenzyloxy)-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane of the formula (I) any of its individual enantiomers or any non-racemic mixture thereof, comprising the steps of  

This invention relates to a process for the epoxidation of a tetrasubstituted alkene such as terpinolene to the corresponding epoxide such as terpinolene epoxide by reacting the tetrasubstituted alkene with peracetic acid prepared in situ from acetic anhydride and hydrogen peroxide in the presence of at least one buffering agent. Further, the invention relates to the use of an oxidizing agent comprising hydrogen peroxide and acetic anhydride for the in-situ epoxidation of a tetrasubstituted alkene.

The present invention relates to a process for the preparation of the compounds II from the respective oxo compounds. Furthermore, he invention relates to a process for the preparation of triazole compounds from oxiranes II.

The present invention relates to a process for providing substituted phenyl ketones. Furthermore, the invention relates to the use of substituted phenoxyphenyl ketones obtained by the inventive process for the preparation of triazoles.

Process for the preparation of substituted phenyl ketones

The present invention relates to a process for the preparation of the ketone compounds (IA) and their use as intermediates for the preparation of triazole fungicides.

Process for the preparation of substituted phenoxyphenyl ketones

The present invention relates to a process for the preparation of oxirane compounds of formula II from keto compounds III using dimethyl sulfide (CH)S and dimethylsulfate (CH)SO, forming the reagent IV, trimethylsulfonium methylsulfate [(CH)SCHSO], in aqueous solution in the presence of potassium hydroxide (KOH).

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Wachenheim, Germany

Joachim Gebhardt