Bracco Diagnostics Inc.

Bracco International Bv

Bracco Research, USA

Bracco Suisse Sa

Jo Anna Monteferrante

Julius P Zodda

Ernst Schramm

Ernest Balestracci

Charles R Quirico

James A Melchore, Jr

Irene K Ropiak

Margaret Newborn

Ernest Schramm

Irene Kucharewicz Ropiak

Thomas Katona

Edmund C Metcalfe

Irene Ropiak

Gregory W White

Gregory White

Jules Zodda

James A Melchore

A radioisotope generator system can include a column assembly having a column, an inlet arm, an outlet arm. The column can contain packing material that binds a radioisotope. In addition, the column may define a notch between an open area and a stopper receptacle area in which an opening of the outlet arm is positioned. In some examples, the system includes a Luer lock connection between the outlet arm and a connector tubing. The Luer lock connection can include a male Luer cap and a female Luer cap each comprising tabs configured to line up with or overlap each other so as to indicate when the caps are sufficiently tightened together so as to form a non-leaking lock.

Containers for pharmaceuticals, particularly for use in radioisotope generators

The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator.

The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formulations, as well as methods for treating, preventing, and diagnosing gall bladder-related disorders using sincalide formulations.

Sincalide formulations

A kit containing a solution of boronic acid adducts of technetium-99 m dioxime complexes; and hydroxypropyl gamma cyclodextrin to maintain the solution free of particulate matter originating from the formulation.

Kit for the preparation of technetium TC 99m teboroxime myocardial

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Flemington, NJ, United States of America

Jo Anna Monteferrante