Astrazeneca Ab

Jörgen Funder Rasmussen

Henrik Hougaard Vilstrup

Nicholas Bowman

Jörgen Fruensgaard

Keld Sloth Christensen

In an exemplary embodiment, a breath actuated inhaler (BAI) actuator may include a loading element capable of being loaded with an actuation force and a breath actuated trigger mechanism arranged to counteract the actuation force of the loading element and to fire the actuator by releasing the actuation force of the loading element in response to an inhalation breath. An actuation locking device may be moveable between a locked position wherein it relieves the actuation force from the trigger mechanism setting the trigger mechanism in a neutral position, and an armed position wherein the trigger mechanism is set in an armed position.

Inhaler 624

The disclosure relates to an Breath actuated inhaler (BAI) actuator, comprising: a loading element capable of being loaded with an actuation force, a breath actuated trigger mechanism arranged to counteract the actuation force of the loading element, and to fire the actuator by releasing the actuation force of the loading element in response to an inhalation breath, and actuation locking device moveable between a locked position wherein it relieves the actuation force from the trigger mechanism setting the trigger mechanism in a neutral position, and an armed position wherein the trigger mechanism is set in an armed position.

The present invention relates to an Breath actuated inhaler (BAI) actuator, comprising: a loading element capable of being loaded with an actuation force, a breath actuated trigger mechanism arranged to counteract the actuation force of the loading element, and to fire the actuator by releasing the actuation force of the loading element in response to an inhalation breath, and actuation locking means moveable between a locked position wherein it relieves the actuation force from the trigger mechanism setting the trigger mechanism in a neutral position, and an armed position wherein the trigger mechanism is set in an armed position.

An inhaler for delivery by inhalation of a medicament from the canister which is compressible to deliver a dose of medicament. The inhaler comprises a housing () for holding a canister () having a generally cylindrical body () with the cylindrical axis of the body () in predetermined direction and a loading mechanism for loading a resilient loading element () which is arranged, when loaded, to bias compression of the canister (). The loading mechanism comprises a loading member () engaging the resilient loading element () and two contact members () movable relative to the housing () in a movement direction orthogonal to said predetermined direction and arranged to drive the loading member () to load the resilient loading element (), through a cam arrangement between the contact member (). The cam arrangement may allow for the ratio of the amount of driven movement of the loading member () to the amount of mount of the contact members () to be non-linear, preferably reducing over the driven movement to compensate for the increasing resistance by the resilient loading element.

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Struer, Denmark

Jörgen Funder Rasmussen