Miami University

Jnanendra K Bhattacharjee

Vasker Bhattacherjee

Paul Luther Skatrud

Robert Brown Peery

Richard C Garrad

Kalavati Suvarna

The present invention provides novel methods and materials for detecting the presence of a fungus in a biological sample. The inventive methods and materials exploit the fact that the amino acid sequence of the &agr;-aminoadipate reductase molecule is highly conserved in fungi. Inventive hybridization probes, nucleic acids, PCR primers, antibodies, epitopes, reagents and methods are provided.

Reagents and kits for detecting fungal pathogens in a biological sample

The present invention provides novel methods and materials for detecting the presence of a fungus in a biological sample. The inventive methods and materials exploit the fact that the amino acid sequence of the saccharopine dehydrogenase molecule is highly conserved in fungi. Inventive hybridization probes, nucleic acids, PCR primers, antibodies, epitopes, reagents and methods are provided.

Methods and reagents for detecting fungal pathogens in a biological

The present invention provides materials and methods for sensitively and selectively screening biological samples for the presence of Candida albicans, a fungal pathogen of increasing clinical concern. Specifically, nucleic acids, reagents, and primers for DNA amplification are provided that will allow amplification of a 526 base pair oligonucleotide from DNA containing Candida albicans. Methods for using such primers in DNA amplification are also provided.

Growing community of inventors

Oxford, OH, United States of America

Jnanendra K Bhattacharjee