University of Texas System

Pohang University of Science and Technology Foundation

Jiyong Lee

Zhenpeng Qin

Luxi Chen

Jonghae Youn

Peiyuan Kang

Hyun-Suk Lim

Chao Long

Maria Castaneda

The present disclosure provides a for peptoid compounds that bind selective to cancer stem cells (CSCs), particularly those associated with breast cancer. Conjugates of the peptoids to detactable labels and therapeutic agent are contemplated as are methods of diagnosing and treating breast cancer.

Synthetic binder of breast cancer stem cells

In one aspect, the present disclosure provides a compound of the formula: In another aspect, the present disclosure also provides methods of preparing the compound disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compound disclosed herein. Additionally, methods of treating cancer with the compound disclosed herein are described.

FOXC2 inhibitor and methods of use thereof

Growing community of inventors

Richardson, TX, United States of America

Jiyong Lee