Ningxia Eppen Biotech Co., Ltd

Heilongjiang Eppen New Materials Co., Ltd.

Jiyin Ma

Yun Zhang

Yong Fang Liang

Tingyi Wen

Shuwen Liu

Gang Meng

Xiuling Shang

Huiping Jia

Fengyong Ma

Aiying Wei

Yong Liang

Daihuan Li

Chunguang Zhao

Xiaowei Guo

Jinlong Chen

Lipeng Yang

Rui Ren

A method for producing L-lysine by fermentation, comprising modifying a gene for coding an NCBI reference sequence NP_601029.1 and/or NP_599350.1 on abacterial chromosome to enable the activity and/or expression quantity of NP_601029.1 and/or NP_599350.1 to be reduced; replacing a promoter of one or more genes on thebacterial chromosome with a EP5 promoter, and fermenting bacteria obtained by modification to produce L-lysine. Also provided are methods and applications derived from the method, and bacteria and promoter that can used in the methods and the applications.

for producing L-lysine by fermentation

Corynebacterium for producing L-lysine by fermentation

A method for fermentation-production of a pentanediamine, comprising: culturing a cell expressing a lysine decarboxylase to obtain a whole cell fermentation broth comprising a pentanediamine; and extracting the pentanediamine from the whole cell fermentation broth, and striping the whole cell fermentation broth of carbon dioxide contained therein before adding a strong base. The method greatly increases a production volume of the pentanediamine.

Method for fermentation-production of pentanediamine comprising carbon dioxide stripping technique

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Ningxia, China

Jiyin Ma